Electrospun regenerated silk fibroin mats with enhanced mechanical properties
Electrospun regenerated silk fibroin mats with enhanced mechanical properties
复制标题
具有增强机械性能的静电纺再生丝素蛋白垫
DOI：
10.1016/j.ijbiomac.2013.01.033
复制
发表时间：
2013-05-01
影响因子：
8.2
通讯作者：
Hu, Xuechao
中科院分区：
文献类型：
--
作者：
Fan, Suna;Zhang, Yaopeng;Hu, Xuechao
采用一种简单有效的方法对再生丝素(RSF)水溶液电纺毡进行强化处理。首先在90vol.%乙醇水溶液中机械拉伸垫子，然后在相同的溶液中浸泡30分钟。采用扫描电子显微镜(SEM)、拉曼光谱、广角X射线衍射仪(WAXD)、差示扫描量热仪(DSC)和拉伸试验研究了不同拉伸速率和拉伸倍数的RSF板坯的形态、结构、热性能和力学性能。结果表明，随着拉伸倍数的增加，纤维的β-折叠构象、结晶度和沿拉伸方向排列的纤维数量明显增加。在1.4倍拉伸倍数和0.1 mm/S拉伸倍数下，后处理板坯的断裂强度和断裂能分别为8.6兆帕和172.2 J/kg。然而，初生垫分别只有1.8兆帕和93.2J/kg。由全水溶液制备的增强型RSF垫可能在组织工程中有广泛的应用。(C)2013爱思唯尔B.V.保留所有权利。
In this paper, a simple and effective method was applied to enhance regenerated silk fibroin (RSF) mats electrospun from aqueous solution. The mats were first mechanically drawn in 90 vol.% ethanol aqueous solution and then immersed in the same solution for 30 min. The morphology, structure, thermal and mechanical properties of the RSF mats with different draw rates and draw ratios were investigated by scanning electron microscope (SEM), Raman spectroscopy, wide angle X-ray diffraction (WAXD), differential scanning calorimetry (DSC) and tensile test. Results revealed that the content of beta-sheet conformation, the crystallinity and the number of fibers aligned to the drawing direction increased evidently with the draw ratio. The breaking strength and breaking energy of the post-treated mats at 1.4x draw ratio and 0.1 mm/s draw rate were 8.6 MPa and 172.2 J/kg, respectively. However, those of the as-spun mats were only 1.8 MPa and 93.2 J/kg, respectively. The enhanced RSF mats prepared from entirely aqueous solutions may have extensive applications for tissue engineering. (c) 2013 Elsevier B.V. All rights reserved.