Effects of iron deficiency on neonatal behavior at different stages of pregnancy
Effects of iron deficiency on neonatal behavior at different stages of pregnancy
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DOI：
10.1016/j.earlhumdev.2010.12.006
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发表时间：
2011-03-01
影响因子：
2.5
通讯作者：
Arija, Victoria
中科院分区：
文献类型：
--
作者：
Hernandez-Martinez, Carmen;Canals, Josefa;Arija, Victoria
动物和人类研究表明，产前和产后缺铁是行为，情感和认知发展的危险因素。本研究的目的是确定孕妇的铁状况与新生儿的行为之间的关联，同时考虑到赤字发生的时间。这项研究是在西班牙（发达国家）进行的，那里的一般人口营养良好;在怀孕期间进行例行产科检查;孕妇系统地补充铁。共有216名健康和营养良好的孕妇及其足月体重正常的新生儿参加了这项研究。采用新生儿行为评定量表（NBAS）评定新生儿行为。结果表明，在怀孕的第一和第二个三个月，铁缺乏是一个弱的和显着的预测NBAS自主神经系统集群得分，并在第三个三个三个月，这种条件预测NBAS运动和状态组织集群得分和NBAS健壮性和耐力补充项目。总之，孕期铁缺乏与新生儿的一般自主反应、运动表现和自我调节能力有关。(C)2011爱思唯尔爱尔兰有限公司保留所有权利。
Animal and human studies have shown that prenatal and postnatal iron deficiency is a risk factor for behavioral, emotional and cognitive development. The aim of this study was to determine the associations between iron status of pregnant women and the behavior of their newborn, taking into account the timing in which the deficit occurs. This study was conducted in Spain (developed country) where: the general population is well-nourished; during pregnancy routine obstetrical checks are carried out; and pregnant women are systematically iron supplemented. A total of 216 healthy and well-nourished pregnant women and their term, normal weight newborn participated in this study. The neonatal behavior was assessed by the Neonatal Behavior Assessment Scale (NBAS). The results showed that in the first and second trimesters of pregnancy, iron deficiency was a weak and significant predictor of the NBAS autonomous nervous system cluster score, and in the third trimester, this condition predicted the NBAS motor and state organization clusters score and the NBAS robustness and endurance supplementary item. In conclusion, iron deficiency during pregnancy is related to the neonate's general autonomous response, motor performance and self regulation capabilities. (C) 2011 Elsevier Ireland Ltd. All rights reserved.