Alkylative Amination of Biogenic Furans through Imine-to-Azaallyl Anion Umpolung
Alkylative Amination of Biogenic Furans through Imine-to-Azaallyl Anion Umpolung
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DOI：
10.1055/s-0034-1380201
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发表时间：
2015-07-01
影响因子：
2.6
通讯作者：
Deska, Jan
中科院分区：
文献类型：
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作者：
Blume, Fabian;Albeiruty, Mhd Haitham;Deska, Jan
Starting from biogenic furfurals, an operationally simple and scalable condensation-umpolung-alkylation protocol was employed in the synthesis of racemic furfurylamines. Subsequent enzymatic kinetic resolution by -transaminase or lipase biocatalysts allows for the preparation of functionalized heterocyclic building blocks from biogenic base chemicals in optically pure form.
