A behavioral analysis of the ingestion of glucose, maltose and maltooligosaccharide by rats
A behavioral analysis of the ingestion of glucose, maltose and maltooligosaccharide by rats
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DOI：
10.1016/s0031-9384(99)00265-6
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发表时间：
2000-06-01
影响因子：
2.9
通讯作者：
Breslin, PAS
中科院分区：
文献类型：
--
作者：
Davis, JD;Breslin, PAS
葡萄糖、麦芽糖和多糖是刺激大鼠摄食的有效性不同的刺激物。为了更好地了解葡萄糖链长度的变化如何影响这些化合物的摄入，我们比较了Si？葡萄糖、麦芽糖和麦芽低聚糖（MOS）浓度对大鼠舔体行为显微结构的影响。在三个最低浓度下，刺激摄食的有效性顺序为MOS >麦芽糖>葡萄糖。在三个最高浓度下，三种化合物的摄入量无差异。以舔体初始速率为指标，3种化合物对小鼠口腔感觉刺激的效果顺序为甘露醇>麦芽糖>葡萄糖。负反馈信号的幅度对于MOS和麦芽糖非常相似，并且除了最高的两种葡萄糖浓度之外，都大于葡萄糖，这表明葡萄糖链长度而不是热量密度是负反馈幅度差异的原因。在三个最低浓度下，化合物刺激摄入能力的顺序取决于orosensory刺激能力。(C)2000 Elsevier Science Inc. All rights reserved.
Glucose, maltose, and Polycose are stimuli that differ in their effectiveness in stimulating ingestion in the rat. To understand better how variation in glucose chain length affects the ingestion of these compounds, we compared the effect of si?; concentrations of glucose, maltose, and maltooligosaccharide (MOS) on the microstructure of the licking behavior of the rat. At the three lowest concentrations the order of effectiveness in stimulating ingestion was MOS > maltose > glucose. At the three highest concentrations, there were no differences among the three compounds in volume ingested. As measured by initial rate of licking, the orosensory stimulating effectiveness of the three compounds were ordered as MOS > maltose > glucose. The magnitude of the negative feedback signals were very similar for MOS and maltose and greater than glucose at all but the highest two concentrations of glucose, suggesting that glucose chain length, not caloric density, is responsible for the differences in the magnitude of negative feedback. With the three lowest concentrations, the ordering of the compounds in their ability to stimulate intake depended on orosensory stimulating ability. (C) 2000 Elsevier Science Inc. All rights reserved.