Relationships between the Chemical Structure and Mutagenic Activity of Monocyclic Aromatic Amines
Relationships between the Chemical Structure and Mutagenic Activity of Monocyclic Aromatic Amines
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单环芳香胺的化学结构与诱变活性的关系
DOI：
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发表时间：
1983
期刊：
影响因子：
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通讯作者：
G. Kalopissis
中科院分区：
文献类型：
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作者：
M. Shahin;A. Bugaut;G. Kalopissis
数以百计的化合物现在已经在世界各地的许多实验室进行了突变活性测试。进行致突变性测试是为了验证各种检测系统，并为化学品的毒理学安全性评估做出贡献。遗传毒理学的一个研究领域对开发安全的化学产品具有重要意义，那就是研究一系列同源化合物，以便将化学结构与遗传活性联系起来。
Hundreds of compounds have now been tested for mutagenic activity in many laboratories throughout the world. Mutagenicity tests are performed to validate a variety of assay systems and to contribute to the toxicological safety evaluation of chemicals. An area of research in genetic toxicology that has important implications for the development of safe chemical products is the study of series of homologous compounds in order to relate chemical structure to genetic activity.