Prevalence of depression and its treatment in an elderly population -: The Cache County study
Prevalence of depression and its treatment in an elderly population -: The Cache County study
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DOI：
10.1001/archpsyc.57.6.601
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发表时间：
2000-06-01
影响因子：
--
通讯作者：
Breitner, JCS
中科院分区：
文献类型：
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作者：
Steffens, DC;Skoog, I;Breitner, JCS
背景：以前对老年抑郁症患病率的估计有所不同。很少有大规模的基于人群的研究；其中大部分针对 80 岁以下的人。自新型抗抑郁药问世以来，美国尚未发表任何研究。 方法：从 1995 年到 1996 年，作为一项大型人口研究的一部分，我们调查了 4559 名年龄在 65 岁至 100 岁的非痴呆个体中当前和终生抑郁症的患病率。该样本代表了犹他州卡什县 90% 的老年人口。使用诊断访谈计划的修改版本，我们确定了过去和现在的 DSM-IV 重度抑郁症、心境恶劣和亚临床抑郁症。药物使用情况是通过结构化访谈和“药箱清单”确定的。结果：重度抑郁症的患病率估计女性为 4.4%，男性为 2.7% (P=0.003)。其他抑郁综合征出人意料地罕见（综合点患病率为 1.6%）。在目前患有重度抑郁症的受试者中，35.7% 正在服用抗抑郁药（主要是选择性血清素再摄取抑制剂），27.4% 正在服用镇静/催眠药。目前重度抑郁症的患病率并没有随着年龄的增长而发生明显变化。据估计，女性终生重性抑郁患病率为 20.4%，男性为 9.6%（P
Background: Previous estimates of the prevalence of geriatric depression have varied. There are few large population-based studies; most of these focused on individuals younger than 80 years. No US studies have been published since the advent of the newer antidepressant agents.Methods: In 1995 through 1996, as part of a large population study, we examined the current and lifetime prevalence of depressive disorders in 4559 nondemented individuals aged 65 to 100 years. This sample represented 90% of the elderly population of Cache County, Utah. Using a modified version of the Diagnostic Interview Schedule, we ascertained past and present DSM-IV major depression, dysthymia, and subclinical depressive disorders. Medication use was determined through a structured interview and a "medicine chest inventory."Results: Point prevalence of major depression was estimated at 4.4% in women and 2.7% in men (P=.003). Other depressive syndromes were surprisingly uncommon (combined point prevalence, 1.6%). Among subjects with current major depression, 35.7% were taking an antidepressant (mostly selective serotonin reuptake inhibitors) and 27.4% a sedative/hypnotic. The current prevalence of major depression did not change appreciably with age. Estimated lifetime prevalence of major depression was 20.4% in women and 9.6% in men (P