Filamentous influenza viruses.
Filamentous influenza viruses.
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DOI:
10.1099/jgv.0.000535
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发表时间:
2016-08
期刊:
影响因子:
--
通讯作者:
Hutchinson EC
中科院分区:
文献类型:
--
作者:
Dadonaite B;Vijayakrishnan S;Fodor E;Bhella D;Hutchinson EC
Clinical isolates of influenza virus produce pleomorphic virus particles, including extremely long filamentous virions. In contrast, strains of influenza that have adapted to laboratory growth typically produce only spherical virions. As a result, the filamentous phenotype has been overlooked in most influenza virus research. Recent advances in imaging and improved animal models have highlighted the distinct structure and functional relevance of filamentous virions. In this review we summarise what is currently known about these strikingly elongated virus particles and discuss their possible roles in clinical infections.
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DOI:
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