Attention‐deficit/hyperactivity disorder: The past 50 years

Attention‐deficit/hyperactivity disorder: The past 50 years
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注意力缺陷/多动障碍:过去 50 年

DOI:
10.1111/jpc.12809
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发表时间:
2015
影响因子:
1.7
通讯作者:
D. Efron
D. Efron
中科院分区:
医学4区
文献类型:
--
作者:
D. Efron

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注意力缺陷多动障碍(ADHD)是一种常见的神经发育障碍,也是当今普通儿科医生的主要诊断之一。尽管媒体经常描绘这种印象,但它并不是一种新的情况;事实上,它已经描述了200多年。在过去的50年里,我们对多动症潜在神经认知缺陷的了解不断增加,在过去的20年里,行为遗传学和神经影像学研究揭示了复杂的因果因素和神经生物学过程的运作。过多的ADHD研究促进了我们对这种情况的了解,但到目前为止,对改善临床实践几乎没有影响。刺激性药物已经成为对症治疗的支柱超过30年;然而,仍然不清楚如何修改发育轨迹以实现最佳结果。人们希望在未来几十年内,新的治疗方法和更个性化的管理将得到发展。
Attention‐deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder and one of the main diagnoses seen by general paediatricians today. Despite the impression often portrayed in the media, it is not a new condition; in fact it has been described for over 200 years. The past 50 years has seen a progressive increase in our understanding of the underlying neurocognitive deficits in ADHD, and over the past 20 years behavioural genetics and neuroimaging studies have shed light on the complex causal factors and neurobiological processes operating. The plethora of ADHD research has advanced our knowledge of the condition, but so far has had little impact on improving clinical practice. Stimulant medication has been the mainstay of symptomatic treatment for over 30 years; however, it is still unclear how developmental trajectories can be modified to achieve best outcomes. It is hoped that novel therapies and more individualised management will evolve over the coming decades.
DOI: 10.12968/hmed.2010.71.11.79663
发表时间: 2018-05
影响因子: 0.9
作者:
Muhammed Ather;G. Salmon
通讯作者: Muhammed Ather;G. Salmon
DOI: 10.1093/ije/dyt261
发表时间: 2014-04-01
影响因子: 7.7
作者:
Polanczyk, Guilherme V.;GWillcutt, Erik;Rohde, Luis A.
通讯作者: Rohde, Luis A.