Consensus conference: Colorectal cancer screening and surveillance in inflammatory bowel disease
Consensus conference: Colorectal cancer screening and surveillance in inflammatory bowel disease
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DOI：
10.1097/01.mib.0000160811.76729.d5
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发表时间：
2005-03-01
影响因子：
4.9
通讯作者：
Present, DH
中科院分区：
文献类型：
--
作者：
Itzkowitz, SH;Present, DH
特发性炎症性肠病，溃疡性结肠炎和克罗恩氏结肠炎，与患结直肠癌的风险增加有关。为了降低炎症性肠病中结直肠癌的死亡率，大多数患者及其医生选择遵循监测结肠镜检查计划，以在可治愈阶段检测早期肿瘤病变。结肠切除术通常保留给活检结果表明病理学家基于油解释的癌症风险增加的患者。尽管缺乏前瞻性对照临床试验来正式评估这种方法的益处、风险和成本，但已经积累了足够的间接证据来证明其在实践中的广泛采用。然而，还没有标准化的指南来指导胃肠病学家进行监测。一个国际专家小组被召集起来，为监督的执行提出共识建议。本文介绍了调查结果。
The idiopathic inflammatory bowel diseases, ulcerative colitis and Crohn's colitis, are associated with an increased risk for developing colorectal cancer. To reduce colorectal cancer mortality in inflammatory bowel disease, most patients and their physicians choose to follow a program of Surveillance colonoscopy in ail attempt to detect early neoplastic lesions at a curable stage. Colectomy is typically reserved for patients whose biopsy findings are indicative of heightened cancer risk based oil interpretation by pathologists. Despite the absence of prospective controlled clinical trials to formally evaluate the benefits, risks, and costs of this approach, enough circumstantial evidence has accrued to warrant its widespread adoption in practice. Nevertheless, no standardized guidelines have yet been Set forth to guide the gastroenterologist in performing Surveillance. A panel of international experts was assembled to develop consensus recommendations for the performance Of surveillance. The findings are presented herein.