Cone-Beam CT with a Flat-Panel Detector: From Image Science to Image-Guided Surgery.
Cone-Beam CT with a Flat-Panel Detector: From Image Science to Image-Guided Surgery.
复制标题
DOI：
10.1016/j.nima.2010.11.088
复制
发表时间：
2011-08-21
期刊：
影响因子：
--
通讯作者：
Siewerdsen JH
中科院分区：
文献类型：
--
作者：
Siewerdsen JH
大面积平板X射线探测器（FPD）的发展促进了对先进医学成像应用的研究，包括断层合成和锥形束CT（CBCT）。最近的研究已经扩展了图像质量指标和理论模型，这些应用，提供了一个定量的基础，评估成像性能，以及一个通用的框架，设计，优化和翻译这些技术的新应用。例如，傅立叶域度量的级联系统模型，例如噪声等效量子（NEQ），已经被扩展到这些模态，以描述信号和噪声通过图像采集和重建链的传播，并量化控制空间分辨率、图像噪声和可检测性的因素。此外，这样的模型已经证明了与人类观察者的表现，为广泛的成像条件和成像任务的基本协议。图像科学的这些发展为CBCT在图像引导介入中的知识开发和新应用的转化奠定了基础-例如，CBCT在移动的手术C形臂上实施，用于术中3D成像。在手术干预期间按需获取高质量3D图像的能力克服了仅在术前图像的背景下手术引导的传统限制。学术界与工业界合作开发的原型移动的C形臂展示了CBCT的低辐射剂量、亚毫米级空间分辨率和软组织可见性，可能接近诊断CT。3D成像系统与实时跟踪、可变形配准、内窥镜视频和3D可视化的集成为从头颈/颅底手术到脊柱、骨科、胸部和腹部手术的手术库提供了一个有前途的补充。尸体研究表明，CBCT引导下的手术性能有可能显著提高，早期临床试验证明了手术室内的可行性、工作流程和图像质量。
The development of large-area flat-panel x-ray detectors (FPDs) has spurred investigation in a spectrum of advanced medical imaging applications, including tomosynthesis and cone-beam CT (CBCT). Recent research has extended image quality metrics and theoretical models to such applications, providing a quantitative foundation for the assessment of imaging performance as well as a general framework for the design, optimization, and translation of such technologies to new applications. For example, cascaded systems models of Fourier domain metrics, such as noise-equivalent quanta (NEQ), have been extended to these modalities to describe the propagation of signal and noise through the image acquisition and reconstruction chain and to quantify the factors that govern spatial resolution, image noise, and detectability. Moreover, such models have demonstrated basic agreement with human observer performance for a broad range of imaging conditions and imaging tasks. These developments in image science have formed a foundation for the knowledgeable development and translation of CBCT to new applications in image-guided interventions - for example, CBCT implemented on a mobile surgical C-arm for intraoperative 3D imaging. The ability to acquire high-quality 3D images on demand during surgical intervention overcomes conventional limitations of surgical guidance in the context of preoperative images alone. A prototype mobile C-arm developed in academic-industry partnership demonstrates CBCT with low radiation dose, sub-mm spatial resolution, and soft-tissue visibility potentially approaching that of diagnostic CT. Integration of the 3D imaging system with real-time tracking, deformable registration, endoscopic video, and 3D visualization offers a promising addition to the surgical arsenal in interventions ranging from head-and-neck / skull base surgery to spine, orthopaedic, thoracic, and abdominal surgeries. Cadaver studies show the potential for significant boosts in surgical performance under CBCT guidance, and early clinical trials demonstrate feasibility, workflow, and image quality within the surgical theatre.
登录
查看更多内容
影响因子：
--
作者：
Khoury, A.;Siewerdsen, J. H.;Jaffray, D. A.
通讯作者：
Jaffray, D. A.
影响因子：
3.8
作者：
Khoury, Amal;Whyne, Cari M.;Jaffray, David
通讯作者：
Jaffray, David
DOI：
10.1016/s0360-3016(02)02884-5
发表时间：
2002-08-01
影响因子：
7
作者：
Jaffray, DA;Siewerdsen, JH;Martinez, AA
通讯作者：
Martinez, AA
影响因子：
3.8
作者：
Fahrig, Rebecca;Dixon, Robert;Strobel, Norbert
通讯作者：
Strobel, Norbert
影响因子：
3.8
作者：
Chen, GH
通讯作者：
Chen, GH