Smoking topography: Reliability and validity in dependent smokers
Smoking topography: Reliability and validity in dependent smokers
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DOI：
10.1080/1462220031000158645
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发表时间：
2003-10-01
影响因子：
4.7
通讯作者：
Pickworth, WB
中科院分区：
文献类型：
--
作者：
Lee, EM;Malson, JL;Pickworth, WB
对两项研究的数据进行了分析，以确定通过地形装置的烟嘴吸烟是否会随着时间的推移产生一致的测量结果，并验证通过烟嘴吸烟导致的烟雾暴露程度与传统吸烟相似。在这两项研究中，受试者随意吸他们常用品牌的香烟。在研究 A 中，受试者 (n = 7) 在 4 个独立的实验日通过烟嘴吸烟。在研究 B 中，受试者 (n = 10) 在 2 个不同的日子里吸烟：一次是常规吸烟，一次是通过烟嘴吸烟。在这两项研究中，都测量了吸烟前后呼出的一氧化碳（CO）和生理效应（心率和血压）。在研究 B 中，还测量了血浆尼古丁浓度。在研究 A 中，抽吸量、抽吸持续时间、抽吸间隔和最大抽吸速度平均分别为 30.8 毫升、0.9 秒、19.9 秒和 44.6 毫升/秒。计算抽吸量 (0.66)、抽吸持续时间 (0.75) 和最大抽吸速度 (0.68) 的组内相关系数表明，这些测量显示出良好的可靠性。在研究 B 中，通过烟嘴吸烟产生与传统吸烟相似的地形测量（吸烟时间和每支烟的抽吸次数）。生化值的变化也相似：传统吸烟条件和地形烟嘴吸烟条件下的血浆尼古丁（18.5 ng/ml vs. 25.5 ng/ml）、呼出的 CO（4.6 ppm vs. 5.1 ppm）和心率（8.6 次/分钟 vs. 7.4 次/分钟）。两项研究之间的地形测量没有显着差异。总体而言，这两项小样本研究的数据表明，吸烟地形提供了传统吸烟的有效且可靠的指标以及烟雾暴露的间接测量。
Data from two studies were analyzed to determine whether smoking through the mouthpiece of a topography unit yields consistent measures over time and to verify that smoking through a mouthpiece results in a similar degree of smoke exposure as conventional smoking. In both studies, subjects smoked their usual brand of cigarette ad libitum. In study A, subjects (n = 7) smoked through a mouthpiece on 4 separate experimental days. In study B, subjects (n = 10) smoked on 2 separate days: Once conventionally and once through a mouthpiece. In both studies, exhaled carbon monoxide (CO) and physiological effects (heart rate and blood pressure) were measured before and after smoking. In study B, plasma nicotine concentrations also were measured. In study A, puff volume, puff duration, interpuff interval, and maximum puff velocity averaged 30.8 ml, .9 s, 19.9 s, and 44.6 ml/s, respectively. Intraclass correlation coefficients computed for puff volume (0.66), puff duration (0.75), and maximum puff velocity (0.68) indicated that these measures showed good reliability. In study B, smoking through the mouthpiece yielded similar topographical (time to smoke and number of puffs per cigarette) measures as conventional smoking. Also similar were changes in biochemical values: Plasma nicotine (18.5 ng/ml vs. 25.5 ng/ml), exhaled CO (4.6 ppm vs. 5.1 ppm), and heart rate (8.6 beats/min vs. 7.4 beats/min) for conventional and topography mouthpiece smoking conditions, respectively. Topography measures did not differ significantly between the two studies. Overall, the data from these two small-sample studies suggest that smoking topography provides a valid and reliable index of conventional smoking and an indirect measure of smoke exposure.