Neuroanatomical Correlates of Morphine Dependence
Neuroanatomical Correlates of Morphine Dependence
复制标题
吗啡依赖性的神经解剖学相关性
作者：
E. Wei;H. Loh;E. Way
盐酸纳洛酮是一种阿片类拮抗剂，应用于吗啡依赖大鼠的几个离散的脑区，以沉淀戒断。给药后，在丘脑中引起重度戒断体征，但在大脑的新皮质、海马、下丘脑或被盖区中未引起。
Naloxone hydrochloride, an opioid antagonist, was applied to several discrete brain regions of morphine-dependent rats to precipitate abstinence. Severe withdrawal signs were elicited after administration in the thalamus but not in neocortical, hippocampal, hypothalamic, or tegmental areas of the brain.