Incretin-based therapies are associated with acute pancreatitis: Meta-analysis of large randomized controlled trials
Incretin-based therapies are associated with acute pancreatitis: Meta-analysis of large randomized controlled trials
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DOI：
10.1016/j.diabres.2015.10.014
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发表时间：
2015-12-01
影响因子：
5.1
通讯作者：
Dennis, Brittany B.
中科院分区：
文献类型：
--
作者：
Roshanov, Pavel S.;Dennis, Brittany B.
关于肠促胰岛素类口服降糖药对急性胰腺炎风险的影响，以往的研究提供了微弱且相互矛盾的证据。这项对最近三项大型试验的荟萃分析发现，与常规治疗相比，使用这些药物的急性胰腺炎几率增加了82%（95%CI，1.17-2.82）。(C)2015爱思唯尔爱尔兰有限公司版权所有。
Previous studies have offered weak and conflicting evidence regarding the impact of incretin-based oral antihyperglycemic agents on risk of acute pancreatitis. This meta-analysis of three recent mega-trials found an 82% increase in the odds of acute pancreatitis with the use of these agents compared to usual care (95% CI, 1.17-2.82). (C) 2015 Elsevier Ireland Ltd. All rights reserved.