A 128-Channel 6 mW Wireless Neural Recording IC With Spike Feature Extraction and UWB Transmitter
A 128-Channel 6 mW Wireless Neural Recording IC With Spike Feature Extraction and UWB Transmitter
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DOI：
10.1109/tnsre.2009.2021607
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发表时间：
2009-08-01
影响因子：
4.9
通讯作者：
Liu, Wentai
中科院分区：
文献类型：
--
作者：
Chae, Moo Sung;Yang, Zhi;Liu, Wentai
本文报道了一种128通道神经记录集成电路（IC），具有即时锋电位特征提取和无线遥测功能。该芯片由8个16通道前端记录模块、尖峰检测和特征提取数字信号处理器（DSP）、超宽带（UWB）发射器和片内偏置发生器组成。每个记录通道都有可编程增益和带宽的放大器，以适应不同类型的生物信号。通过时分复用由16个放大器共享的模数转换器（ADC）导致功耗和芯片面积之间的平衡折衷。实现了基于非线性能量算子（NEO）的尖峰检测器用于识别尖峰，尖峰由数字频率成形滤波器进一步处理。计算效率高的尖峰检测和特征提取算法归因于一个吉祥的DSP芯片上实现。UWB遥测被设计为以90 Mbit/s的数据速率从128个记录通道无线传输原始数据。该芯片是实现在0.35 μ m的互补金属氧化物半导体（CMOS）工艺与8.8 - 7.2毫米（2）的面积和消耗6毫瓦通过采用顺序导通架构，选择性地关闭空闲的模拟电路块。该芯片已经过电气规格测试，并在离体生物环境中进行了验证。
This paper reports a 128-channel neural recording integrated circuit (IC) with on-the-fly spike feature extraction and wireless telemetry. The chip consists of eight 16-channel front-end recording blocks, spike detection and feature extraction digital signal processor (DSP), ultra wideband (UWB) transmitter, and on-chip bias generators. Each recording channel has amplifiers with programmable gain and bandwidth to accommodate different types of biological signals. An analog-to-digital converter (ADC) shared by 16 amplifiers through time-multiplexing results in a balanced trade-off between the power consumption and chip area. A nonlinear energy operator (NEO) based spike detector is implemented for identifying spikes, which are further processed by a digital frequency-shaping filter. The computationally efficient spike detection and feature extraction algorithms attribute to an auspicious DSP implementation on-chip. UWB telemetry is designed to wirelessly transfer raw data from 128 recording channels at a data rate of 90 Mbit/s. The chip is realized in 0.35 mu m complementary metal-oxide-semiconductor (CMOS) process with an area of 8.8 7.2 mm(2) and consumes 6 mW by employing a sequential turn-on architecture that selectively powers off idle analog circuit blocks. The chip has been tested for electrical specifications and verified in an ex vivo biological environment.