Visualization of the lenticulostriate arteries at 3T using black-blood T1-weighted intracranial vessel wall imaging: comparison with 7T TOF-MRA
Visualization of the lenticulostriate arteries at 3T using black-blood T1-weighted intracranial vessel wall imaging: comparison with 7T TOF-MRA
复制标题
使用黑血 T1 加权颅内血管壁成像在 3T 下观察豆纹动脉：与 7T TOF-MRA 的比较
DOI：
10.1007/s00330-018-5701-y
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发表时间：
2019-03-01
影响因子：
5.9
通讯作者：
Zhuo, Yan
中科院分区：
文献类型：
--
作者：
Zhang, Zihao;Fan, Zhaoyang;Zhuo, Yan
目的本研究的目的是探讨使用颅内 T1 加权血管壁成像 (VWI) 在 3T 下可视化豆纹动脉 (LSA) 的可行性。 材料和方法 13 名健康志愿者在同一天接受 3T 下的 VWI 和 7T 下的 TOF-MRA 检查。在手工追踪获得的血管骨架上，统计LSA的茎和分支的数量。在每个半球最突出的分支上，测量并比较两种方法的对比度噪声比 (CNR)、全长和局部长度（MCA 上方 5-15 毫米）。九名患有颅内动脉狭窄的中风患者也被纳入该研究。比较有症状侧和无症状侧的LSA分支。结果提取的血管树在7T TOF-MRA和3T VWI上吻合良好。两次收购的 LSA 茎数量相似。 3T VWI 显示的分支数量略低于 7T TOF。根据 VWI 在 3T 时的全长略低（p = 0.011，ICC = 0.917）。测量的局部长度（距 MCA 5-15 毫米）显示 VWI 和 TOF-MRA 之间具有高度一致性（p = 0.098，ICC = 0.970）。在中风患者中，MCA 节段上发现了 12 个斑块，其中 9 个斑块位于有症状的一侧。 3T VWI 可视化的 LSA 平均数量为有症状侧 4.3±1.3 个，无症状侧 5.0±1.1 个。结论 3T VWI 能够描绘 LSA，特别是茎和近端节段，其图像质量与 7T TOF-MRA 相当。要点• 3T 时 T1 加权颅内 VWI 允许进行黑血 MR 血管造影 豆纹动脉。• 3T 颅内 VWI 描绘豆纹动脉的干部和近端段，与 7T TOF-MRA 相当。• 在一次扫描中评估大血管壁病变和豆纹血管病变是可行的。
ObjectivesThe objective of this study was to explore the feasibility of using intracranial T1-weighted vessel wall imaging (VWI) to visualize the lenticulostriate arteries (LSAs) at 3T.Material and methodsThirteen healthy volunteers were examined with VWI at 3T and TOF-MRA at 7T during the same day. On the vascular skeletons obtained by manual tracing, the number of stems and branches of LSAs were counted. On the most prominent branch in every hemisphere, the contrast-to-noise ratio (CNR), the full length and the local length (5-15 mm above MCAs) were measured and compared between the two methods. Nine stroke patients with intracranial artery stenosis were also recruited into the study. The branches of LSAs were compared between the symptomatic and asymptomatic side.ResultsThe extracted vascular trees were in good agreement between 7T TOF-MRA and 3T VWI. The two acquisitions showed similar numbers of the LSA stems. The number of branches revealed by 3T VWI was slightly lower than 7T TOF. The full lengths were slightly lower by VWI at 3T (p= 0.011, ICC = 0.917). The measured local lengths (5-15 mm from MCAs) showed high coherence between VWI and TOF-MRA (p= 0.098, ICC = 0.970). In stroke patients, 12 plaques were identified on MCA segments, and nine plaques were located on the symptomatic side. The average numbers of LSA visualized by 3T VWI were 4.3±1.3 on the symptomatic side and 5.0±1.1 on the asymptomatic side.Conclusion3T VWI is capable of depicting LSAs, particularly the stems and the proximal segments, with comparable image quality to that of 7T TOF-MRA.Key Points• T1-weighted intracranial VWI at 3T allows for black-blood MR angiography of lenticulostriate artery.• 3T intracranial VWI depicts the stems and proximal segments of the lenticulostriate arteries comparable to 7T TOF-MRA.• It is feasible to assess both large vessel wall lesions and lenticulostriate vasculopathy in one scan.