A pilot study of impulsivity and compulsivity in pathological gambling
A pilot study of impulsivity and compulsivity in pathological gambling
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DOI：
10.1016/j.psychres.2008.04.023
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发表时间：
2009-05-15
影响因子：
11.3
通讯作者：
Grant, Jon E.
中科院分区：
文献类型：
--
作者：
Blanco, Carlos;Potenza, Marc N.;Grant, Jon E.
我们研究了38名病理性赌徒的赌博严重程度、冲动性和强迫/强迫性之间的关系，这些赌徒代表了一项帕罗西汀治疗病理性赌博（PG）的随机、安慰剂对照临床试验的完整明尼苏达州样本，在基线和治疗终点使用Pearson相关性和线性回归模型。在基线时，耶鲁-布朗强迫症量表（PG-YBOCS）的病理赌博修正评分与艾森克冲动问卷（EIQ）冲动子量表和帕多瓦量表（PI）因子I和IV（分别对应于对精神和运动活动的控制受损）的评分显著相关。PI因素和PG-YBOCS之间的关联在调整冲动评分后均不显著。帕罗西汀组和安慰剂组之间的PG-YBOCS变化无差异。治疗后PG-YBOCS评分的变化与冲动评分的变化相关。这些变化似乎与帕罗西汀治疗无关。结果表明，虽然PG表现出的强迫症/强迫性和冲动性的特点，这两个因素减少治疗，冲动占主导地位，赌博的严重程度的变化与冲动性的变化最相关。(C)2008年由Elsevier爱尔兰有限公司出版。
We examined the relationship between gambling severity, impulsivity and obsessionality/compulsivity in 38 pathological gamblers, representing the complete Minnesota sample of a randomized, placebo-controlled clinical trial of paroxetine for the treatment of pathological gambling (PG), using Pearson correlations and linear regression models at baseline and treatment endpoint. At baseline, Pathological Gambling Modification of the Yale-Brown Obsessive-Compulsive Scale (PG-YBOCS) scores correlated significantly with those of the Eysenck Impulsiveness Questionnaire (EIQ) Impulsiveness subscale and Padua Inventory (PI) factors I and IV (corresponding to impaired control over mental and motor activities, respectively). None of the associations between PI factors and the PG-YBOCS were significant after adjusting for Impulsiveness scores. There were no differences in changes in the PG-YBOCS between the paroxetine and placebo group. Changes in PG-YBOCS scores after treatment correlated with changes in Impulsiveness scores. These changes appeared independent of paroxetine treatment. The results suggest that, although PG exhibits features of both obsessionality/compulsivity and impulsivity and elements of both decrease with treatment, impulsivity predominates and changes in gambling severity are most associated with changes in impulsivity. (C) 2008 Published by Elsevier Ireland Ltd.