Complete Genome Sequences of Three Historically Important, Spatiotemporally Distinct, and Genetically Divergent Strains of Zika Virus: MR-766, P6-740, and PRVABC-59.

Complete Genome Sequences of Three Historically Important, Spatiotemporally Distinct, and Genetically Divergent Strains of Zika Virus: MR-766, P6-740, and PRVABC-59.
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DOI:
10.1128/genomea.00800-16
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发表时间:
2016-08-18
期刊:
Genome announcements
影响因子:
--
通讯作者:
Lee YM
Lee YM
中科院分区:
其他
文献类型:
--
作者:
Yun SI;Song BH;Frank JC;Julander JG;Polejaeva IA;Davies CJ;White KL;Lee YM

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在这里,我们报告了三种时空上不同且遗传上不同的寨卡病毒株的10,807个核苷酸长的共有RNA基因组序列,其基因组序列的功能性通过反向遗传学得到证实:MR-766(非洲谱系,乌干达,1947)、P6-740(亚洲谱系,马来西亚,1966)和PRVABC-59(亚洲谱系衍生的美国菌株,波多黎各,2015)。
Here, we report the 10,807-nucleotide-long consensus RNA genome sequences of three spatiotemporally distinct and genetically divergent Zika virus strains, with the functionality of their genomic sequences substantiated by reverse genetics: MR-766 (African lineage, Uganda, 1947), P6-740 (Asian lineage, Malaysia, 1966), and PRVABC-59 (Asian lineage-derived American strain, Puerto Rico, 2015).