Cellulose-supported copper(0) catalyst for aza-Michael addition

Cellulose-supported copper(0) catalyst for aza-Michael addition
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DOI:
10.1055/s-2006-949623
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发表时间:
2006-09-01
期刊:
影响因子:
2
通讯作者:
Kumar, Nadakudity S.
Kumar, Nadakudity S.
中科院分区:
化学4区
文献类型:
--
作者:
Reddy, K. Rajender;Kumar, Nadakudity S.

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纤维素负载的铜(0)有效地催化N-亲核试剂如胺和咪唑与α,β-不饱和化合物的氮杂-迈克尔反应,以优异的产率产生相应的β-氨基化合物和N-取代的咪唑。反应是容易的,并且回收的催化剂用于几个循环,具有一致的活性。
Cellulose-supported copper(0) efficiently catalyzes the aza-Michael reaction of N-nucleophiles, such as amines and imidazoles with alpha,beta-unsaturated compounds to produce the corresponding beta-amino compounds and N-substituted imidazoles in excellent yields. The reactions are facile and the recovered catalyst is used for several cycles with consistent activity.