Application of machine vision to assess involved surface in patients with psoriasis

Application of machine vision to assess involved surface in patients with psoriasis
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应用机器视觉评估银屑病患者受累表面

DOI:
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发表时间:
1997
影响因子:
10.3
通讯作者:
A. Oikarinen
A. Oikarinen
中科院分区:
医学1区
文献类型:
--
作者:
L. Savolainen;J. Kontinen;J. Röning;A. Oikarinen

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银屑病严重程度的定量评价尚缺乏客观的方法。本研究的目的是探讨一种新的彩色分割方法的计算机图像分析(CIA)是否可以作为估计银屑病患者累及表面面积的客观方法。来自不同医学专业团体和CIA的人类观察员对26名患者的银屑病涉及的表面面积进行了评估,这些彩色照片覆盖了与银屑病面积和严重程度指数(PASI)评分相同的区域。通过参考分析,在投影幻灯片的辅助下,对图像中涉及的区域进行人工着色,测试了CIA的可靠性。对不同方法估计的表面积进行了比较,并评估了对PASI评分的影响。参考分析与图像分析的一致性较高,尤其是躯干区域,但四肢的圆柱形导致在评估受累皮肤面积时存在一定困难。在几乎三分之一的病例中,人眼的估计与图像分析的估计不同,而且大多数情况下,牛皮癣影响的皮肤表面积低于30%。高估和低估都有出现,但高估更为常见。误差估计对PASI评分有显著影响。中央情报局的方法似乎是可靠和实用的估计牛皮癣的实际表面。该方法的缺点是耗时(拍摄、处理图片)和技术要求高。这种方法的进一步发展应该会使它在未来更快。
An objective method is still lacking in the quantitative assessment of psoriasis severity. The purpose of this study was to examine whether computer image analysis (CIA) by a new colour segmentation method can be used as an objective method of estimating involved surface area in patients with psoriasis. Involved surface area in psoriasis was assessed from colour photographs covering the same areas as the psoriasis area and severity index (PASI) scores of 26 patients by human observers from different medical professional groups and by CIA. The reliability of CIA was tested with reference analysis by colouring manually the involved areas in the images with the aid of projected slides. The surface area estimates by the different methods were compared with each other and the resulting effects on the PASI score were assessed. The agreement between the reference analysis and the image analysis was high, especially on trunk areas, but the cylindrical shape of the limbs resulted in some difficulties in assessing involved skin area. The human eye estimates differed from the image analysis ones in almost one‐third of the cases and mostly when psoriasis affected under 30% of the skin surface area. Both over‐and underestimates emerged, but overestimates were more common. Error estimates had a significant effect on the PASI score. The CIA method seems to be reliable and practicable in estimating the actual surface of psoriasis. The method has the disadvantage of being time‐consuming (photographing, processing of pictures) and technically demanding. Further development of this method should make it faster in the future.