The Objective Physical Activity and Cardiovascular Disease Health in Older Women (OPACH) Study.
The Objective Physical Activity and Cardiovascular Disease Health in Older Women (OPACH) Study.
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DOI：
10.1186/s12889-017-4065-6
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发表时间：
2017-02-14
影响因子：
4.5
通讯作者：
Herring AH
中科院分区：
文献类型：
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作者：
LaCroix AZ;Rillamas-Sun E;Buchner D;Evenson KR;Di C;Lee IM;Marshall S;LaMonte MJ;Hunt J;Tinker LF;Stefanick M;Lewis CE;Bellettiere J;Herring AH
有限的证据存在，以告知身体活动（PA）和久坐不动的行为指南，为老年人，特别是妇女。需要严格的证据来证明与晚年健康状况改善相关的运动量、强度和运动模式。客观PA和心血管健康（OPACH）研究是妇女健康倡议（WHI）计划的辅助研究，该计划检查了加速度计评估的PA和久坐行为与心血管和跌倒事件的关联。2012年至2014年期间，为7048名63-99岁的女性提供了ActiGraph GT3 X+（彭萨科拉，佛罗里达）三轴加速度计、睡眠日志和OPACH PA问卷; 6489名有加速度计数据。大多数女性年龄在70多岁（40%）或80多岁（46%），而大约10%的女性年龄在60多岁，4%的女性年龄在90岁或以上。非西班牙裔黑人或西班牙裔/拉丁裔妇女占该群体的一半。随访包括为期1年的福尔斯跌倒监测，每月日历和电话访谈跌倒者，以及每年随访结果，直至2020年裁定心血管疾病（CVD）事件。5,776名妇女返回了63,600多个月的日历页，报告了5,980次福尔斯。对1 492名妇女进行了电话采访，以确定与跌倒有关的情况、受伤情况和医疗护理。该数据集包含与健康老龄化相关的表型的广泛信息，包括炎症和CVD生物标志物，乳腺癌和结肠癌，髋关节和其他骨折，糖尿病和身体残疾。本文描述了作为OPACH研究一部分的在自由生活条件下佩戴加速度计的绝经后妇女的不同队列的研究设计、方法和基线数据。通过使用加速度计收集更精确和完整的数据PA和久坐行为在一个大的队列的老年妇女，这项研究将提供关键的新证据，多少，如何积极的，什么样的模式PA是必要的，以保持最佳的心血管健康，并避免福尔斯在以后的生活。ClinicalTrials.gov标识符NCT 00000611。1999年10月27日登记。本文的在线版本（doi：10.1186/s12889-017-4065-6）包含补充材料，可供授权用户使用。
Limited evidence exists to inform physical activity (PA) and sedentary behavior guidelines for older people, especially women. Rigorous evidence on the amounts, intensities, and movement patterns associated with better health in later life is needed. The Objective PA and Cardiovascular Health (OPACH) Study is an ancillary study to the Women’s Health Initiative (WHI) Program that examines associations of accelerometer-assessed PA and sedentary behavior with cardiovascular and fall events. Between 2012 and 2014, 7048 women aged 63–99 were provided with an ActiGraph GT3X+ (Pensacola, Florida) triaxial accelerometer, a sleep log, and an OPACH PA Questionnaire; 6489 have accelerometer data. Most women were in their 70s (40%) or 80s (46%), while approximately 10% were in their 60s and 4% were age 90 years or older. Non-Hispanic Black or Hispanic/Latina women comprise half of the cohort. Follow-up includes 1-year of falls surveillance with monthly calendars and telephone interviews of fallers, and annual follow-up for outcomes with adjudication of incident cardiovascular disease (CVD) events through 2020. Over 63,600 months of calendar pages were returned by 5,776 women, who reported 5,980 falls. Telephone interviews were completed for 1,492 women to ascertain the circumstances, injuries and medical care associated with falling. The dataset contains extensive information on phenotypes related to healthy aging, including inflammatory and CVD biomarkers, breast and colon cancer, hip and other fractures, diabetes, and physical disability. This paper describes the study design, methods, and baseline data for a diverse cohort of postmenopausal women who wore accelerometers under free-living conditions as part of the OPACH Study. By using accelerometers to collect more precise and complete data on PA and sedentary behavior in a large cohort of older women, this study will contribute crucial new evidence about how much, how vigorous, and what patterns of PA are necessary to maintain optimal cardiovascular health and to avoid falls in later life. ClinicalTrials.gov identifier NCT00000611. Registered 27 October 1999. The online version of this article (doi:10.1186/s12889-017-4065-6) contains supplementary material, which is available to authorized users.