Broadband miniature optical ultrasound probe for high resolution vascular tissue imaging
Broadband miniature optical ultrasound probe for high resolution vascular tissue imaging
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DOI：
10.1364/boe.6.001502
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发表时间：
2015-04-01
影响因子：
3.4
通讯作者：
Desjardins, Adrien E.
中科院分区：
文献类型：
--
作者：
Colchester, Richard J.;Zhang, Edward Z.;Desjardins, Adrien E.
研制了一种用于血管组织成像的全光超声探头。超声波是通过脉冲激光照射光纤端面上的功能化碳纳米管复合涂层而产生的。利用相邻光纤端面上的法布里-珀罗(FP)腔检测超声。探头直径为0.84 mm，超声带宽接近20 MHz。该探头在组织样本上平移以产生超声发射/接收元件的虚拟线性阵列。在3.5 mm深度，用碳纤维靶测量，轴向分辨率为微米，横向分辨率为88微米。对猪的血管组织进行了体外成像，观察到与组织学有很好的一致性。(C)2015年美国光学学会
An all-optical ultrasound probe for vascular tissue imaging was developed. Ultrasound was generated by pulsed laser illumination of a functionalized carbon nanotube composite coating on the end face of an optical fiber. Ultrasound was detected with a Fabry-Perot (FP) cavity on the end face of an adjacent optical fiber. The probe diameter was < 0.84 mm and had an ultrasound bandwidth of similar to 20 MHz. The probe was translated across the tissue sample to create a virtual linear array of ultrasound transmit/receive elements. At a depth of 3.5 mm, the axial resolution was 64 mu m and the lateral resolution was 88 mu m, as measured with a carbon fiber target. Vascular tissues from swine were imaged ex vivo and good correspondence to histology was observed. (C) 2015 Optical Society of America