Individuals With Agenesis of the Corpus Callosum Show Sensory Processing Differences as Measured by the Sensory Profile
Individuals With Agenesis of the Corpus Callosum Show Sensory Processing Differences as Measured by the Sensory Profile
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DOI：
10.1037/neu0000165
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发表时间：
2015-09-01
期刊：
影响因子：
2.4
通讯作者：
Marco, Elysa
中科院分区：
文献类型：
--
作者：
Demopoulos, Carly;Arroyo, Monica S.;Marco, Elysa
目的：鉴于报告的高痛阈和减少的听觉反应的胼胝体发育不全（AgCC）的个人，本研究调查是否受影响的参与者报告非典型的经验和行为的一个完善的感觉处理措施。方法：14名AgCC参与者（年龄11-59岁）完成了青少年/成人感觉特征（Brown & Dunn，2001）。如果感觉特征量表与平均值的标准差大于1，则将其归类为“非典型”。结果：57%的AgCC参与者报告感觉注册减少，而预期的正常样本为16%。同样，50%的AgCC参与者报告听觉处理困难增加。结论：使用一个完善的感觉处理问卷，参与者与AgCC报告可测量的差异，在多个方面的感觉处理。最显着的差异是在象限的低感觉注册，这表明个人与AgCC可能需要感官信息，以更慢或更高的强度，以充分的处理。受影响最大的感觉方式是听觉系统，这与该人群中语言障碍和自闭症谱系障碍的发病率增加一致。了解与AgCC个人的感觉处理既可以阐明的作用，半球间转移的发展完整的感觉处理，以及有助于我们的知识的胼胝体的作用，在一系列的疾病，其中感觉过程受到影响。
Objective: Given reports of high pain thresholds and reduced auditory response in individuals with agenesis of the corpus callosum (AgCC), this study investigated whether affected participants report atypical experiences and behaviors on a well-established sensory processing measure. Methods: Fourteen participants with AgCC (ages 11-59) completed the Adolescent/Adult Sensory Profile (Brown & Dunn, 2001). Sensory profile scales were classified as "Atypical" if they were more than 1 standard deviation from the mean. Results: Fifty-seven percent of participants with AgCC reported reduced sensory registration as compared to an expected 16% of the normative sample. Similarly, 50% of the AgCC participants reported atypically increased auditory processing difficulties. Conclusions: Using a welle-stablished sensory processing questionnaire, participants with AgCC reported measurable differences in multiple aspects of sensory processing. The most notable difference was in the quadrant of low sensory registration, suggesting that individuals with AgCC may require sensory information to be presented more slowly or at a higher intensity for adequate processing. The sensory modality that was most affected was the auditory system, which is consistent with increased rates of language disorders and autism spectrum disorders in this population. Understanding sensory processing in individuals with AgCC can both elucidate the role of interhemispheric transfer in the development of intact sensory processing as well as contribute to our knowledge of the role of the corpus callosum in a range of disorders in which sensory processes are impacted.