AuI/AuIII Catalysis: An Alternative Approach for C -C Oxidative Coupling
AuI/AuIII Catalysis: An Alternative Approach for C -C Oxidative Coupling
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DOI：
10.1002/chem.201100736
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发表时间：
2011-07-01
影响因子：
4.3
通讯作者：
Gouverneur, Veronique
中科院分区：
文献类型：
--
作者：
Hopkinson, Matthew N.;Gee, Antony D.;Gouverneur, Veronique
当在外部氧化剂存在下反应时，金配合物能够催化氧化均偶联和交叉偶联反应，涉及新C-C键的形成。在过去的几年中，已经报道了几个级联过程，其中偶合之前是金介导的芳基C-H官能化或亲核加成。这些反应联合收割机将金的独特反应性与氧化偶联结合起来，使得能够在偶联配偶体之间构建使用替代催化剂不容易接近的C-C键。在这篇概念论文中，讨论了金催化氧化偶联反应的发展，重点是广泛的合成吸引力的C-C键形成反应。
When reacted in the presence of external oxidants, gold complexes are capable of catalyzing oxidative homo-and cross-coupling reactions involving the formation of new C-C bonds. Over the last few years, several cascade processes have been reported in which coupling is preceded by a gold-mediated aryl C-H functionalization or nucleophilic addition. These reactions combine the unique reactivity of gold with oxidative coupling, enabling the construction of C-C bonds between coupling partners that are not easily accessed using alternative catalysts. In this Concept paper, the development of gold-catalyzed oxidative coupling reactions is discussed focusing on C-C bond-forming reactions of broad synthetic appeal.