Anterolateral Thigh Flap in a Chicken Model: A Novel Perforator Training Model
Anterolateral Thigh Flap in a Chicken Model: A Novel Perforator Training Model
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DOI：
10.1055/s-0039-1679882
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发表时间：
2019-09-01
影响因子：
2.1
通讯作者：
Colonna, Michele Rosario
中科院分区：
文献类型：
--
作者：
Costa, Alfio Luca;Cucinotta, Filippo;Colonna, Michele Rosario
临床前训练通常在活体动物模型上进行；然而，由于道德和/或经济限制，这些模型不可能进行重复训练。我们描述了一种使用鸡大腿的前外侧大腿皮瓣（ALT皮瓣）训练模型，该模型似乎是一种合适的训练模型，例如，在活鼠或猪模型中培养穿孔皮瓣。方法采用10只鸡腿作为实验材料。解剖六只鸡腿，以确认穿支的存在，并确定主要的血管树。在四条鸡腿上，基于穿支计划皮瓣，并在放大下进行肌内剥离。结果在所有解剖中均发现穿支，在髌骨至股骨头第三近端线以上3cm处均发现穿支。近端动脉和静脉平均直径分别为0.56 （sigma = 0.04）和0.84 (sigma = 0.06) mm。提升皮瓣的平均剥离时间为88 (sigma = 7) min。结论本文首次描述了一种模拟ALT皮瓣的穿支皮瓣剥离训练的非活体生物模拟模型。作为离体鸡模型，它是一种成本效益高、易于获得、适合重复实践的模型。
Background Preclinical training in perforator flap harvesting is typically conducted on living animal models; however, repeated training is not possible with these models because of ethical and/or economical constraints. We describe an anterolateral thigh flap (ALT flap) training model using chicken thigh that seems to be an appropriate training model prior, for example, to raise a perforator flap in a living rat or swine model. Methods A total of 10 chicken legs were used in this study. Six chicken legs were anatomically dissected to confirm the presence of the perforator and to identify the main vascular tree. In four chicken legs, a skin flap was planned based on the perforator and intramuscular dissection was performed under magnification. Results The perforator was identified in all dissections and was consistently found 3 cm above the line extending from the patella to the head of the femur in its third proximal. Proximally, the mean diameter of the artery and vein was 0.56 (sigma = 0.04) and 0.84 (sigma = 0.06) mm, respectively. The mean dissection time to raise the flap was 88 (sigma = 7) min. Conclusion This is the first description of a nonliving biological simulation model for training in perforator flap dissection that mimics an ALT flap. As an ex vivo chicken model, it is a cost effective and readily accessible model suitable for repeated practice.