Pulmonary adenocarcinoma of fetal type: alternating differentiation argues in favour of a common endodermal stem cell
Pulmonary adenocarcinoma of fetal type: alternating differentiation argues in favour of a common endodermal stem cell
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胎儿型肺腺癌：交替分化支持共同的内胚层干细胞
DOI：
10.1007/bf00708328
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
E. Kaiserling
中科院分区：
文献类型：
--
作者：
H. Müller;E. Kaiserling
肺腺癌表现出不同的细胞类型，从超微结构上看，这些细胞类型似乎与终末肺小叶中出现的不同上皮细胞类型有关。本文描述了一种新定义的肺腺癌的光学显微镜、超微结构和免疫组织化学特征，该类型类似于肺分化的早期阶段。该肿瘤内交替的上皮分化表明肺内不同类型的上皮细胞（包括内分泌细胞）有共同的内胚层干细胞。讨论了该肿瘤与肺母细胞瘤的关系。
Pulmonary adenocarcinoma exhibit different cell types that ultrastructurally, appear to be related to the different epithelial cell types occuring in the terminal lung lobule. The present paper describes the light-microscopical, ultrastructural and immunhistochemical features of a newly defined type of pulmonary adenocarcinoma that resembles an early stage of lung differentiation. The alternating epithelial differentiation within this tumour speaks in favour of a common endodermal stem cell for the different types of epithelial cells within the lung, including endocrine cells. The relationship of this tumour to pulmonary blastoma is discussed.
表面活性剂脱辅基蛋白和克拉拉细胞抗原在化学诱导和自然发生的小鼠肺肿瘤中的免疫细胞化学定位。
DOI：
--
发表时间：
1985
期刊：
The American journal of pathology
影响因子：
--
作者：
Ward,JM;Singh,G;Katyal,SL;Anderson,LM;Kovatch,RM
通讯作者：
Kovatch,RM