Evaluation of body composition parameters in patients with psoriasis
Evaluation of body composition parameters in patients with psoriasis
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DOI：
10.1111/ijd.12171
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发表时间：
2014-12-01
影响因子：
3.6
通讯作者：
Tuzun, Yalcin
中科院分区：
文献类型：
--
作者：
Engin, Burhan;Kutlubay, Zekayi;Tuzun, Yalcin
研究背景身体成分参数，如体重、体重指数（BMI）和内脏脂肪评分，已被发现与银屑病相关。然而，这些参数与银屑病的相关性尚未得到证实。ObjectivesThis study aims to evaluate body composition parameters in patients with psoriasis.MethodsThe relationships between the various body composition parameters and psoriasis was retrospectively examined in 242 patients with plaque psoriasis（119 women，123 men）over a 2-year period during 2010-2012.此外，在治疗和未治疗的银屑病患者中评估身体组成参数与银屑病面积和严重程度指数（PASI）评分之间的相关性。根据患者在过去三个月内是否接受过系统治疗，将其分为两组。使用Tanita SC-330身体成分分析仪（R）测量身体成分值。在治疗和未治疗的患者和对照受试者中，记录了体重（kg）、体脂百分比、脂肪质量（kg）、全身水（TBW）百分比、代谢年龄、内脏脂肪评级、BMI和肥胖程度的统计学显著差异。发现无脂肪质量（FFM）（kg）、肌肉质量（kg）、TBW（kg）和骨量（kg）的差异接近显著性限值。治疗组和未治疗组在评估的任何参数方面均无显着差异。PASI评分和各种参数之间的相关性提供了一些证据，这种relationships.ConclusionsThe本研究提供了证据的一些身体成分参数和银屑病的发生之间的关系。我们建议，身体成分参数应分析不仅在肥胖型银屑病患者，但在所有银屑病患者首次诊断。全身治疗似乎不会引起身体组成参数的任何变化。
BackgroundBody composition parameters, such as weight, body mass index (BMI), and visceral fat rating, have been found to be associated with psoriasis. However, the associations of these parameters with psoriasis have not been demonstrated clearly.ObjectivesThis study aimed to evaluate body composition parameters in patients with psoriasis.MethodsThe relationships between the various body composition parameters and psoriasis were retrospectively examined in 242 patients with plaque psoriasis (119 women, 123 men) over a 2-year period during 2010-2012. In addition, the correlations between body composition parameters and Psoriasis Area and Severity Index (PASI) score were evaluated in treated and untreated patients with psoriasis. Patients were divided into two groups according to whether or not they had received systemic therapy within the previous threemonths. Body composition values were measured using the Tanita SC-330 Body Composition Analyzer((R)).ResultsStatistically significant differences were recorded in terms of weight (kg), body fat percentage, fat mass (kg), total body water (TBW) percentage, metabolic age, visceral fat rating, BMI, and degree of obesity among treated and untreated patients and control subjects. Differences in fat-free mass (FFM) (kg), muscle mass (kg), TBW (kg), and bone mass (kg) were found to be close to the limit for significance. The treated and untreated groups showed no significant differences in any of the parameters evaluated. The correlations between PASI score and the various parameters provided some evidence for such relationships.ConclusionsThe present study provides evidence of a relationship between some body composition parameters and the occurrence of psoriasis. We suggest that body composition parameters should be analyzed not only in obese psoriasis patients but in all psoriasis patients upon their first diagnosis. Systemic therapy does not appear to cause any changes in body composition parameters.