Efficient synthesis of new 5-substituted uracil nucleosides useful for linker arm incorporation

Efficient synthesis of new 5-substituted uracil nucleosides useful for linker arm incorporation
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有效合成可用于连接臂掺入的新型 5-取代尿嘧啶核苷

DOI:
10.1039/c39940001997
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发表时间:
1994
期刊:
Journal of The Chemical Society, Chemical Communications
影响因子:
--
通讯作者:
H. Ozaki
H. Ozaki
中科院分区:
--
文献类型:
--
作者:
H. Sawai;A. Nakamura;S. Sekiguchi;Keisuke Yumoto;Masakazu Endoh;H. Ozaki

文献摘要

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5-Substituted uracil nucleosides useful for the attachment of linker arms to nucleic acids are prepared from arabinoaminooxazoline and dimethyl α-bromomethylfumarate in a short reaction sequence without using any protecting groups, and incorporated into oligodeoxyribonucleotides.