A PALPABLE SPLEEN IS NOT NECESSARILY ENLARGED OR PATHOLOGICAL
A PALPABLE SPLEEN IS NOT NECESSARILY ENLARGED OR PATHOLOGICAL
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DOI：
10.5694/j.1326-5377.1986.tb113733.x
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发表时间：
1986-07-07
影响因子：
11.4
通讯作者：
MOLAN, MP
中科院分区：
文献类型：
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作者：
ARKLES, LB;GILL, GD;MOLAN, MP
人们普遍认为，可触及的脾脏在成人人群中总是扩大和病理。本研究的目的是评估这一说法的有效性。作为常规，我们的肝脾研究方案包括肝脏柔韧性，它显示了半隔膜在完全吸气和呼气时的水平，以及脾脏大小和胶体摄取。本文回顾了我科所做的1699 mtc硫胶体肝脾研究。在21例以“脾肿大检查”就诊的患者中，扫描显示脾大小为13厘米或更小。在本组中，至少有两名临床医生证实了脾脏可触性。随访未发现21例患者中18例有脾疾病。在对123例连续肝脾扫描的单独尸检随访中，有100例患者的脾扫描大小为13厘米或更小。这被证明是正常的可靠上限，因为该组98%的脾脏重量为250 g或更少，并且在尸检时正常。本研究表明，可触及的脾脏不一定是肿大或病理性的。
It is widely accepted that a palpable spleen in the adult population is always enlarged and pathological. The aim of this study was to assess the validity of this statement. As a routine, our protocol for liver-spleen studies includes liver pliability, which demonstrates the level of the hemidiaphragms at full inspiration and expiration, as well as splenic size and colloidal uptake. Sixteen hundred 99mTc sulphur colloid liver-spleen studies, which had been performed in our Department, were reviewed. In 21 patients, who had been referred with "splenomegaly for investigation", the scintigraphic splenic size was 13 cm posterior length or less. In this group, splenic palpability was confirmed by at least two clinicians. Follow-up did not reveal any evidence of splenic disease in 18 of the 21 patients. In a separate postmortem follow-up of 123 sequential liver-spleen scans, 100 patients were noted to have a scintigraphic splenic size of 13 cm posterior length or less. This was shown to be reliable upper limit of normal because 98% of spleens in this group weighed 250 g or less and were normal at post-mortem examination. This study demonstrates that a palpable spleen is not necessarily enlarged or pathological.