Barometric pressure and the incidence of pulmonary embolism
Barometric pressure and the incidence of pulmonary embolism
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DOI：
10.1378/chest.128.4.2190
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发表时间：
2005-10-01
期刊：
影响因子：
9.6
通讯作者：
Gorguner, M
中科院分区：
文献类型：
--
作者：
Meral, M;Mirici, A;Gorguner, M
目的：文献报道表明，天气变化可能在静脉血栓性疾病中发挥作用。随着春季肺栓塞（PE）患者的增加，我们研究了大气压（AP）与PE发病率之间的关系，大多数患者通过螺旋CT血管造影诊断，少数患者通过常规肺血管造影和肺扫描诊断。方法：我们回顾性研究了2000年8月至2004年9月期间由肺内科评估的91例诊断为PE的连续患者的图表。我们记录了埃尔祖鲁姆省气象局记录的AP变化。结果：春季（3月，15例，4月，10例，5月，12例）肺栓塞的发生率明显高于其他季节（p < 0.001）;肺栓塞发生率与平均动脉压呈负相关（r = -0.70; p < 0.01）。然而，当平均季节性AP与PE发病率相关时，发现这种关系没有统计学意义（r = -0.66; p = 0.34）。PE的严重程度或死亡率与AP之间没有相关性。结论：PE的发病率在春季AP较低时明显较高。需要进行一项区域性研究以捕获所有PE患者，以证实我们的发现。应调查其他气象因素对血栓栓塞性疾病的影响。
Objectives: Reports in the literature suggest that weather changes may play a role in venous thrombotic disease. An increase in patients with pulmonary embolism (PE) during the spring season led us to investigate the relationship between atmospheric pressure (AP) and the incidence of PE, as diagnosed in most of the patients by helical CT angiography, and in the minority of patients by conventional pulmonary angiography and lung scanning.Methods: We retrospectively investigated the charts of 91 consecutive patients with a diagnosis of PE who were evaluated by the Department of Pulmonary Medicine between August 2000 and September 2004. We documented AP changes as recorded by the Erzurum Provincial Department of Meteorology. Of the 91 patients, the diagnosis of PE was made by helical CT angiography in 84 patients, isotope lung scan in 5 patients, and conventional pulmonary angiography in 2 patients.Results: More patients presented in the spring months (March, n = 15; April, n = 10; and May, n = 12) than during other seasons (p < 0.001). The frequency of PE was inversely related to general average AP (r = -0.70; p < 0.01). When the average seasonal AP was correlated with the incidence of PE, however, the relationship was found to not be statistically significant (r = -0.66; p = 0.34). There was no correlation between the severity of PE or mortality and AP.Conclusions: The incidence of PE was significantly higher in the spring months, when AP was low. A regional study to capture all PE patients will need to be done to confirm our findings. Other meteorologic factors should be investigated regarding their effect on thromboembolic disease.