Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2.
Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2.
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DOI：
10.20411/pai.v5i1.373
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发表时间：
2020-01-01
影响因子：
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通讯作者：
Donskey, Curtis J
中科院分区：
文献类型：
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作者：
Cadnum, Jennifer L;Li, Daniel F;Donskey, Curtis J
背景：受污染的表面是呼吸道病毒（包括SARS-CoV-2）传播的潜在来源。紫外线-C（UV-C）光对RNA和DNA病毒有效，可用于多个用户共享的高接触污染物的去污。方法：美国材料与试验学会标准定量载盘试验方法的改进（ASTM E-2197-11）用于检查UV-C光对在3个地点接种甲氧西林的塑料机场安全箱快速去污的有效性，耐药金黄色葡萄球菌（MRSA）和噬菌体MS 2、PhiX 174和Phi 6，一种用作冠状病毒替代物的包膜RNA病毒。减少3 log 10接种的塑料箱被认为是有效的decontamination.RESULTS：UV-C光管理作为10-，20-，或30-秒的周期在接近一个塑料箱减少污染的每个测试网站，包括垂直和水平表面。30秒的周期符合所有3个测试网站的所有测试生物除噬菌体MS 2，这是减少了大于2 log 10 PFU在每个sites.Conclusions：UV-C光是一个有吸引力的技术，用于快速去污机场安全箱的标准。需要进一步的工作来评估UV-C光在现实环境中的效用，并开发通过UV-C去污过程提供自动移动垃圾箱的方法。
BACKGROUND: Contaminated surfaces are a potential source for spread of respiratory viruses including SARS-CoV-2. Ultraviolet-C (UV-C) light is effective against RNA and DNA viruses and could be useful for decontamination of high-touch fomites that are shared by multiple users.METHODS: A modification of the American Society for Testing and Materials standard quantitative carrier disk test method (ASTM E-2197-11) was used to examine the effectiveness of UV-C light for rapid decontamination of plastic airport security bins inoculated at 3 sites with methicillin-resistant Staphylococcus aureus (MRSA) and bacteriophages MS2, PhiX174, and Phi6, an enveloped RNA virus used as a surrogate for coronaviruses. Reductions of 3 log10 on inoculated plastic bins were considered effective for decontamination.RESULTS: UV-C light administered as 10-, 20-, or 30-second cycles in proximity to a plastic bin reduced contamination on each of the test sites, including vertical and horizontal surfaces. The 30-second cycle met criteria for decontamination of all 3 test sites for all the test organisms except bacteriophage MS2 which was reduced by greater than 2 log10 PFU at each site.CONCLUSIONS: UV-C light is an attractive technology for rapid decontamination of airport security bins. Further work is needed to evaluate the utility of UV-C light in real-world settings and to develop methods to provide automated movement of bins through a UV-C decontamination process.