Typhoid fever as a rare cause of hepatic, splenic, and bone marrow granulomas

Typhoid fever as a rare cause of hepatic, splenic, and bone marrow granulomas
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DOI:
10.2169/internalmedicine.43.436
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发表时间:
2004-05-01
期刊:
影响因子:
1.2
通讯作者:
Aktuglu, Y
Aktuglu, Y
中科院分区:
医学4区
文献类型:
--
作者:
Mert, A;Tabak, F;Aktuglu, Y

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在伤寒病程中,肝脏的常见组织学表现是“非特异性反应性肝炎”。肝肉芽肿(HG)是伤寒的一种罕见并发症。我们介绍两例伴有 HG 的伤寒病例并回顾相关文献。病例1(53岁女性)被发现肝脾肉芽肿。这是英语文献中第一例伤寒伴脾肉芽肿的病例。病例2(66岁男性)除HG外还出现骨髓肉芽肿。应该考虑伤寒可能导致多个器官出现肉芽肿。
During the course of typhoid fever, the usual histologic finding of the liver is "nonspecific reactive hepatitis." Hepatic granuloma (HG) is a rare complication of typhoid fever. We present two cases of typhoid fever with HG and review the relevant literature. Case 1 (a 53-year-old female) was found to have both hepatic and splenic granulomas. This is the first case of typhoid fever with splenic granulomas in the English language literature. Case 2 (a 66-year-old male) developed granulomas in the bone marrow in addition to HG. It should be considered that typhoid fever may lead to granulomas in several organs.