Chemoenzymatic synthesis of GDP-azidodeoxymannoses: non-radioactive probes for mannosyltransferase activity
Chemoenzymatic synthesis of GDP-azidodeoxymannoses: non-radioactive probes for mannosyltransferase activity
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DOI：
10.1039/b807016d
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发表时间：
2008-01-01
影响因子：
4.9
通讯作者：
Macmillan, Derek
中科院分区：
文献类型：
--
作者：
Marchesan, Silvia;Macmillan, Derek
GDP-2-、3-、4-或6-叠氮甘露糖可以使用来自肠道沙门氏菌（Salmonella enterica）的酶GDP-甘露糖焦磷酸化酶（GDP-ManPP）从相应的叠氮甘露糖-1-磷酸和GTP成功地制备，并且可以用作甘露糖基转移酶活性的有用探针。
GDP-2-, 3-, 4- or 6-azidomannoses can be successfully prepared from the corresponding azidomannose-1-phosphates and GTP using the enzyme GDP-Mannosepyrophosphorylase (GDP-ManPP) from Salmonella enterica and mail serve as useful probes for mannosyltransferase activity.