HERITABILITY OF URINE AND PLASMA AMYLASE ACTIVITY
HERITABILITY OF URINE AND PLASMA AMYLASE ACTIVITY
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DOI：
10.1007/bf01874272
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发表时间：
1977-01-01
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影响因子：
--
通讯作者：
PARK, KS
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文献类型：
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作者：
PARK, KS
本文对142名12-16岁男女儿童（包括无血缘关系的双胞胎）进行了尿淀粉酶活性测定。统计学分析显示，在蛋白或血液反应阳性的组中分布不同。均匀样本总体中的对数分布为单峰偏态。**图形 **。= -0.6493）和峰度（β 2 = 3.4917）。总体活动的组内相关系数在MZ双胞胎（50对）中为0.6696（P < 0.001），在DZ双胞胎（22对）中为-0.1299（NS [无显著性]）。在同工酶活性方面，相关性不显著。对36对13-15岁的双生子的血浆进行了类似的检查。总体活性的对数分布为单峰，具有偏度。**图形 **。= 0.2321）和峰度（β 2 = -0.7416）。MZ双生子（29对）和DZ双生子（7对）的组内相关系数分别为0.8413（P < 0.001）和0.3689（NS）。同卵双生子血浆同工酶活性的组内相关系数为0.5490（P < 0.01），而异卵双生子组内相关系数不显著。血浆总淀粉酶活性的亲子相关系数为0.2848（P < 0.05），中亲子相关系数为0.3727（P < 0.05）。亲子回归遗传力为0.5298，中亲子回归遗传力为0.4408。
Urine amylase activity was measured in 142 boys and girls including unrelated twin individuals, aged 12-16 yr. Statistical analysis revealed different distribution in the group with positive protein or blood reaction. Log distribution in a homogeneous sample population was unimodal with a skewness .**GRAPHIC**. = -0.6493) and kurtosis (.beta.2 = 3.4917). Intraclass correlation coefficients of overall activities were 0.6696 (P < 0.001) in MZ twins (50 pairs) and -0.1299 (NS [not significant]) in DZ twins (22 pairs). In the rate of isozyme activity, correlation was nonsignificant. Plasma of 36 twin pairs aged 13-15 yr were similarly examined. Log distribution of overall activity was unimodal with a skewness .**GRAPHIC**. = 0.2321) and kurtosis (.beta.2 = -0.7416). Intraclass correlation coefficients of overall activity were 0.8413 (P < 0.001) in MZ twins (29 pairs) and 0.3689 (NS) in DZ twins (7 pairs). Intraclass correlation of plasma isozyme activity rate was 0.5490 (P < 0.01) in MZ twins, but not significant in DZ twins. Parent-offspring correlation of plasma overall amylase activity was 0.2848 (P < 0.05) and its mid-parent-offspring correlation was 0.3727 (P < 0.05). Heritability was 0.5298 from parent-offspring regression and 0.4408 from mid-parent-offspring regression.