Xerostomia - Etiology, recognition and treatment
Xerostomia - Etiology, recognition and treatment
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DOI：
10.14219/jada.archive.2003.0018
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发表时间：
2003-01-01
影响因子：
3.9
通讯作者：
Moore, PA
中科院分区：
文献类型：
--
作者：
Guggenheimer, J;Moore, PA
背景资料。临床医生可能会遇到以下症状。口干症，通常被称为“口干”，指的是服用药物、有某些结缔组织或免疫紊乱、或接受过放射治疗的患者。当干燥症是唾液流量减少的结果时，可能会发生严重的口腔并发症。综述的研究类型。作者对过去20年来牙科和医学领域的临床和科学报告进行了一项由Index Medicus生成的综述。有关口干症的文献涉及口腔医学、病理学、药理学、流行病学、老年病学、牙科肿瘤学、免疫学和风湿病学。其他主题包括唾液功能生理学和口干症及其并发症的处理。结果。口腔干燥症通常发生在冲洗口腔膜的唾液量减少时。然而，症状的出现可能没有唾液腺产量的明显减少。口干症最常被报道的原因是药物。一些具有不同药理活性的常用处方药被发现会产生口干症的副作用。此外，口干症通常与干燥综合征有关，干燥综合征包括口干、眼干，可能伴有类风湿性关节炎或相关的结缔组织疾病。口干症也是放射治疗的常见并发症。结论及临床意义。口干症是一种不舒服的情况，也是一种常见的口腔症状，患者可能会向牙科医生寻求缓解。口干症的并发症包括龋齿、念珠菌病或假牙使用困难。临床医生需要找出可能的原因(S)，并为患者提供适当的治疗。口干症的治疗通常是姑息的，但可能会对这种情况更严重的并发症有一些保护作用。
Background. Clinicians may encounter symptoms of . xerostomia, commonly called "dry mouth," among patients who take medications, have certain connective tissue or immunological disorders or have been,treated with radiation therapy. When xerostormia is the result of a reduction in salivary flow, significantly oral complications can occur. Types of Studies Reviewed. The authors conducted an Index Medicus-generated review of clinical and scientific reports oxerostomia in the dental and medical the past 20, years. The literature pertaining to xerostomia represented the diciplines of oral medicine, pathology, pharmacology , epidemiology, gerodontology, dental oncology, immunology and rheumatology. Additional topics included the physiology of salivary function and the management of xerostomia and its complications. Results. Xerostomia often develops when the amount of saliva that bathes the oral membranes is reduced. However, symptoms may occur without a measurable reduction in salivary gland output. The most frequently reported cause of xerostomia medications. A number of commonly prescribed drugs with a variety of pharmacological activities have been found to produce xerostomia as a side effect. Additionally, xerostomia often is associated with Sjogren's syndrome, a condition that involves dry mouth and dry eyes and that may be accompanied by rheumatoid arthritis or a related connective tissue disease. Xerostomia also is a frequent complication of radiation therapy. Conclusion and Clinical Implications. Xerostomia is an uncomfortable condition and a common oral complaint for which patients may seek relief from dental practitioners. Complications of xerostomia include dental caries, candidiasis or difficulty with the use of dentures. The clinician needs to identify the possible cause(s) and provide the patient with appropriate treatment. Remedies for xerostomia usually are palliabutive but may some protection from the condition's more significant complications.