HELICOBACTER-PYLORI IN MELBOURNE CHINESE IMMIGRANTS - EVIDENCE FOR ORAL-ORAL TRANSMISSION VIA CHOPSTICKS
HELICOBACTER-PYLORI IN MELBOURNE CHINESE IMMIGRANTS - EVIDENCE FOR ORAL-ORAL TRANSMISSION VIA CHOPSTICKS
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DOI：
10.1111/j.1440-1746.1995.tb01347.x
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发表时间：
1995-09-01
影响因子：
4.1
通讯作者：
HSUHAGE, BHH
中科院分区：
文献类型：
--
作者：
CHOW, TKF;LAMBERT, JR;HSUHAGE, BHH
研究人员对 328 名年龄在 25 岁及以上的墨尔本华人移民（162 名男性和 166 名女性）的代表性人群中的幽门螺杆菌血清流行率进行了研究。人口包括出生在中国/香港（n = 110，33.5%）、越南（n = 79，24.1%）、马来西亚/新加坡（n = 102，31.1%）和其他地方（n = 37，11.3%）的中国人。幽门螺杆菌的总体血清阳性率为59.5%；男性为 60.5%，女性为 58.4%。性别特异性分析显示较高的血清流行率与一些社会人口因素之间存在关联；在男性中，年龄（P < 0.0001）、较低的教育水平（P < 0.002）、吸烟（P < 0.042）、使用抗生素（P < 0.015）和筷子（P < 0.047），在女性中，较低的社会经济地位[教育水平（P < 0.030）、家庭总收入（P < 0.0001）和职业地位(P < 0.0001)]和使用筷子(P < 0.002)。不同出生地的移民之间的血清阳性率存在差异（P < 0.001）；出生在马来西亚/新加坡的人（43.1%）低于出生在中国/香港（68.2%）、越南（68.4%）和其他地方（59.5%）的人。不同出生地的移民的社会人口特征也存在差异。多变量分析显示，墨尔本华人移民中幽门螺杆菌感染的危险因素，男性为年龄（B = 1.081）和出生地（B = 1.769），女性为家庭收入（B = 0.541）和使用筷子（B = 1.654）。这项研究表明，幽门螺杆菌通过口腔途径在人与人之间传播，而民族特定的饮食习惯是一个重要的危险因素。
The Helicobacter pylori seroprevalence in a representative population of 328 Melbourne Chinese immigrants (162 men and 166 women) aged 25 years and older were studied. The population consisted of Chinese people born in China/Hong Kong (n = 110, 33.5%), Vietnam (n = 79, 24.1%), Malaysia/Singapore (n = 102, 31.1%), and elsewhere (n = 37, 11.3%). The overall seroprevalence of H. pylori was 59.5%; 60.5% in men and 58.4% in women. Gender specific analysis showed associations between higher seroprevalence and several socio-demographic factors; in men, age (P < 0.0001), lower education level (P < 0.002), cigarette smoking (P < 0.042), the use of antibiotics (P < 0.015) and chopsticks (P < 0.047), and in women, lower socioeconomical status [education level (P < 0.030), gross household income (P < 0.0001) and occupational status (P < 0.0001)] and use of chopsticks (P < 0.002). Seroprevalence differed between immigrants of various birthplaces (P < 0.001); those born in Malaysia/Singapore (43.1%) were lower than those born in China/Hong Kong (68.2%), Vietnam (68.4%), and elsewhere (59.5%). Immigrants of various birthplaces also differed in their pattern of socio-demographics.Multivariate analyses showed that risk factors for H. pylori infection within the Melbourne Chinese immigrants were, in men, age (B = 1.081) and birthplace (B = 1.769) and, in women, household income (B = 0.541) and use of chopsticks (B = 1.654). This study suggests person-to-person transmission of H. pylori via the oral-oral route with ethno-specific food practices an important risk factor.