Laccases and their applications: a patent review.
Laccases and their applications: a patent review.
复制标题
DOI：
10.2174/187220808783330965
复制
发表时间：
2008-01-01
影响因子：
--
通讯作者：
Alcalde, Miguel
中科院分区：
文献类型：
--
作者：
Kunamneni, Adinarayana;Plou, Francisco J;Alcalde, Miguel
漆酶是一类重要的多铜酶，由于其具有氧化酚类和非酚类木质素相关化合物以及高挥发性环境污染物的能力，近年来受到研究者的广泛关注。这使得这些生物催化剂对于它们在几种生物技术过程中的应用非常有用。这些应用包括工业废水的解毒，主要来自造纸和纸浆、纺织和石化工业、聚合物合成、受污染土壤的生物修复、葡萄酒和饮料的稳定。漆酶还被用作催化剂，用于制造抗癌药物，甚至用作化妆品的成分。最近，漆酶的效用也已应用于纳米生物技术。本文综述了近年来有关漆酶的性质、异源生产、分子克隆和在不同工业领域的应用以及它们在纳米生物技术领域的潜在延伸的重要专利。
Laccases are an interesting group of multi copper enzymes, which have received much attention of researchers in last decades due to their ability to oxidize both phenolic and non-phenolic lignin related compounds as well as highly recalcitrant environmental pollutants. This makes these biocatalysts very useful for their application in several biotechnological processes. Such applications include the detoxification of industrial effluents, mostly from the paper and pulp, textile and petrochemical industries, polymer synthesis, bioremediation of contaminated soils, wine and beverage stabilization. Laccases are also used as catalysts for the manufacture of anti-cancer drugs and even as ingredients in cosmetics. Recently, the utility of laccases has also been applied to nanobiotechnology. This paper reviews recent and important patents related to the properties, heterologous production, molecular cloning, and applications of laccases within different industrial fields as well as their potential extension to the nanobiotechnology area.