Cross-correlation in the auditory coincidence detectors of owls
Cross-correlation in the auditory coincidence detectors of owls
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DOI：
10.1523/jneurosci.1969-08.2008
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发表时间：
2008-08-06
影响因子：
5.3
通讯作者：
Pena, Jose Luis
中科院分区：
文献类型：
--
作者：
Fischer, Brian J.;Christianson, G. Bjoern;Pena, Jose Luis
耳间时差（ITD）在许多听觉功能中起着核心作用，其中最重要的是声音定位。如何计算过渡段的经典模型是由Jeffress（1948）提出的。杰弗里斯模型的一个预测是，计算过渡段的神经元应该表现为交叉相关器。虽然已经报道了ITD计算神经元的类似互相关的特性，但试图表明ITD响应函数的形状是由神经元的频谱调谐决定的，这是互相关的一个核心预测，一直没有成功。利用反向相关分析，我们在谷仓猫头鹰的实验中证明了频谱调谐与计算过渡段神经元的过渡段响应之间的关系是相互相关预测的。此外，我们还证明了由双耳不相关噪声响应推导出的符合检测器响应模型与基于互相关的双耳相互作用是一致的。因此，这些结果与杰弗里斯模型的一个关键原则是一致的。我们的工作提出了两种方法来回答相互关系是否描述了巧合检测器的响应，并证明了在仓鸮中，结果是理论所期望的。
Interaural time difference ( ITD) plays a central role in many auditory functions, most importantly in sound localization. The classic model for how ITD is computed was put forth by Jeffress ( 1948). One of the predictions of the Jeffress model is that the neurons that compute ITD should behave as cross- correlators. Whereas cross- correlation- like properties of the ITD- computing neurons have been reported, attempts to show that the shape of the ITD response function is determined by the spectral tuning of the neuron, a core prediction of cross- correlation, have been unsuccessful. Using reverse correlation analysis, we demonstrate in the barn owl that the relationship between the spectral tuning and the ITD response of the ITD- computing neurons is that predicted by cross- correlation. Moreover, we show that a model of coincidence detector responses derived from responses to binaurally uncorrelated noise is consistent with binaural interaction based on cross- correlation. These results are thus consistent with one of the key tenets of the Jeffress model. Our work sets forth both the methodology to answer whether cross- correlation describes coincidence detector responses and a demonstration that in the barn owl, the result is that expected by theory.