Target Lesion Calcium Arc Influence the Performance of Stenting.
Target Lesion Calcium Arc Influence the Performance of Stenting.
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靶病灶钙弧影响支架植入的效果。
DOI：
10.1115/dmd2017-3455
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
Gu,Linxia
中科院分区：
文献类型：
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作者：
Dong,Pengfei;Lin,Shengmao;Wilson,DavidL;Bezerra,HiramG;Gu,Linxia
经皮冠状动脉介入治疗（PCI）是最常见的血管重建术，在17-35%的PCI患者中发现纤维钙化斑块。随着人口老龄化和他汀类药物治疗的延长，这一数字将会上升。钙化常导致支架扩张和支架错位，增加血栓形成和支架内再狭窄的风险。钙的存在强烈地抑制了支架的性能，这是一个有充分证据的指标。本工作的目标是建立有限元模型，以检查钙弧程度对支架植入结果的影响，如斑块内的应力和应变分布，以及支架植入后的管腔增益。有限元方法是揭示支架扩张机制及其与靶病变相互作用的有效工具，为优化临床效果提供指导。
Percutaneous coronary intervention (PCI) is the most common revascularization procedure, in which, fibrocalcific plaques are found in 17–35% of patients undergoing PCI [1]. Numbers will rise with population aging and prolonged statin treatment. Calcifications often lead to stent under expansion and strut malapposition, with increased risk of thrombosis and in-stent restenosis [2]. Presence of calcium strongly inhibits stent performance, a well-documented metric for outcome [3]. The goal of this work is to develop the finite element models for inspecting the influence of the calcium arc extent on the stenting outcomes, such as the stress and strain distribution within the plaque, and the lumen gain following stenting. Finite element method is an effective tool to reveal the mechanism of the stent expansion and its interaction with target lesion, provide guidance for optimal clinical outcomes.
关于支架手术建模对于预测动脉力学的重要性。
DOI：
10.1115/1.4023094
发表时间：
2012
期刊：
Journal of biomechanical engineering
影响因子：
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作者：
Shijia Zhao;L. Gu;Stacey R. Froemming
通讯作者：
Stacey R. Froemming