CAMPYLOBACTER-JEJUNI ADAPTS TO AEROBIC METABOLISM IN THE ENVIRONMENT
CAMPYLOBACTER-JEJUNI ADAPTS TO AEROBIC METABOLISM IN THE ENVIRONMENT
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DOI：
10.1099/00222615-38-2-145
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发表时间：
1993-02-01
影响因子：
3
通讯作者：
CURRY, A
中科院分区：
文献类型：
--
作者：
JONES, DM;SUTCLIFFE, EM;CURRY, A
空肠弯曲杆菌，当留在血琼脂上很长一段时间，被发现在空气中比在微需氧条件下更好地生存。在空气中培养2-3天后，所有菌株均能在空气中生长。供试空肠在继代培养时可在空气中自由生长，并可在空气中进一步无限期继代。这种有氧代谢的适应伴随着菌落形态的变化和外膜蛋白模式的一些变化，但血清分型反应没有变化。在小鼠体内定殖的能力没有改变，生长细胞的螺旋形态也没有改变。C.空肠在动物肠道外时，不仅涉及球菌形态的变化，而且涉及生物体代谢的根本变化。这些变化可能与培养C所需的技术有关。空肠从食物和环境来源。
Campylobacter jejuni, when left on blood agar for prolonged periods, was found to survive better in air than under micro-aerobic conditions. After a period of 2-3 days in air, all strains of C. jejuni examined grew freely in air on subculture, and could be further subcultured apparently indefinitely in air. This adaptation to aerobic metabolism was accompanied by a change in colony morphology and some changes in outer-membrane protein patterns, but no change in serotyping reactions. The ability to colonise mice was unaltered as was the helical morphology of growing cells. The important survival phase of C. jejuni, when outside the animal gut, involves not only a change to coccal morphology but also fundamental changes in the metabolism of the organism. These changes are likely to be relevant to techniques required for culturing C. jejuni from foods and environmental sources.