Synthesis of 5,6-Dihydropyrazolo[5,1-a]isoquinolines through Indium(III)-Promoted Halocyclizations of N-Propargylic Sulfonylhydrazones
Synthesis of 5,6-Dihydropyrazolo[5,1-a]isoquinolines through Indium(III)-Promoted Halocyclizations of N-Propargylic Sulfonylhydrazones
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通过铟(III)促进的N-炔丙磺酰腙卤环化合成5,6-二氢吡唑并[5,1-a]异喹啉
DOI：
10.1021/acs.orglett.6b00534
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发表时间：
2016-04-01
期刊：
影响因子：
5.2
通讯作者：
Zhan, Zhuang-Ping
中科院分区：
文献类型：
--
作者：
Li, Ren-Hao;Ding, Cheng-Ke;Zhan, Zhuang-Ping
研究了铟（III）促进的N-炔丙基磺酰腙卤环化反应制备5，6-二氢吡唑并[5，1-a]异喹啉的新方法。吡唑和3，4-二氢异喹啉部分通过级联环化反应使用容易组装的开链化合物同步形成。吡唑和3，4-二氢异喹啉部分通过级联环化反应使用容易组装的开链化合物形成。
A novel method for the preparation of 5,6-dihydropyrazolo [5,1-a]isoquinoline via indium(III)-promoted halocyclizations of N-propargylic sulfonylhydrazones has been developed. The pyrazole and 3,4-dihydroisoquinoline moieties were synchronously formed via a cascade cyclization reaction using easily assembled open-chain compounds. The pyrazole and 3,4-dihydroisoquinoline moieties were formed via a cascade cyclization reaction using easily assembled open chain compounds.