The ovarian androgen-producing cells: a 2001 perspective.
The ovarian androgen-producing cells: a 2001 perspective.
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DOI：
10.1023/a:1012700802220
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发表时间：
2002-01-01
影响因子：
8.2
通讯作者：
Magoffin, Denis A
中科院分区：
文献类型：
--
作者：
Magoffin, Denis A
出生后哺乳动物卵巢中的雄激素产生细胞位于卵巢的间质室中。最重要的产生雄激素的间质细胞是内膜细胞和次级间质腺细胞。近年来，关于卵巢雄激素产生细胞的术语存在一些混淆，即“卵泡膜间质”细胞与“卵泡膜”细胞不同。事实上，这些细胞是相同的。Erickson等人[1]使用“卵泡膜-间质细胞”这个名称来描述卵泡膜细胞，卵泡膜细胞是卵巢间质区室中的四种雄激素产生细胞类型之一，与仅在胚胎发育期间存在的初级间质细胞、次级间质腺细胞和位于卵巢门区的类固醇生成细胞一起沿着。为了清楚起见，并根据目前的惯例，术语卵泡膜细胞将在整个审查中使用，是指在卵泡内膜的细胞。
The androgen-producing cells in the postnatal mammalian ovary are located in the interstitial compartment of the ovary. The most important types of androgen-producing interstitial cells are the cells in the theca interna and the cells of the secondary interstitial glands. There has been some confusion in recent years regarding the terminology used to describe the ovarian androgen-producing cells, namely that “theca-interstitial” cells are somehow different from “theca” cells. In fact, these are the same cells. The name “theca-interstitial” was used by Erickson et al. [1] to describe the theca cells as one of the four androgen-producing cell types in the interstitial compartment of the ovary along with primary interstitial cells which are present only during embryonic development, secondary interstitial gland cells, and steroidogenic cells located in the hilar region of the ovary. For the sake of clarity and according to current convention, the term theca cell will be used throughout this review to refer to cells in the theca interna of the ovarian follicle.