HETERONOMOUS DNA
HETERONOMOUS DNA
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DOI：
10.1093/nar/11.12.4141
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发表时间：
1983-01-01
影响因子：
14.9
通讯作者：
PUIGJANER, LC
中科院分区：
文献类型：
--
作者：
ARNOTT, S;CHANDRASEKARAN, R;PUIGJANER, LC
A fibrous form of poly d(A):poly d(T) has a heteronomous secondary structure which is the first to be confirmed for a polynucleotide duplex: although both chains are 101helices, mutually hydrogen-bonded in the standard (Watson-Crick) fasnion, each has a quite different conformation. One chain -- probably poly d(A) -- has C3′-endo-puckered furanose rings characteristic of the A family of polynucleotide secondary structures while the other -- probably poly d(T) -- has the C2′-endo-puckered rings of the B family. Since analogous heteronomous structures could be assumed by DNA-DNA or DNA-RNA duplexes containing more general base sequences the polymorphic range of polynucleotide double-helices may be even greater than we have come to suppose.
