ACCUMULATION OF P-ELEMENTS IN MINORITY INVERSIONS IN NATURAL-POPULATIONS OF DROSOPHILA-MELANOGASTER
ACCUMULATION OF P-ELEMENTS IN MINORITY INVERSIONS IN NATURAL-POPULATIONS OF DROSOPHILA-MELANOGASTER
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DOI：
10.1017/s0016672300030111
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发表时间：
1992-02-01
期刊：
影响因子：
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通讯作者：
CHARLESWORTH, B
中科院分区：
文献类型：
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作者：
EANES, WF;WESLEY, C;CHARLESWORTH, B
内的染色体倒位的转座因子的积累，从理论上研究的数学模型，和经验的计数与倒位多态性在自然种群的黑腹果蝇的P元素。该模型表明，如果一个倒位的杂合性有效地减少了有害染色体重排的元素相关生产，预计元素的差异积累，增加少数倒位内的拷贝数。在一定的参数值下，可能出现几倍的微分积累。我们目前的数据P元素计数倒位多态性的所有5个染色体臂的157个单倍体基因组从两个非洲人口。我们的观察结果表明，显着增加的元素数量与最不常见的，或少数安排，在自然反转多态性的区域内。
The accumulation of a transposable element inside chromosomal inversions is examined theoretically by a mathematical model, and empirically by counts of P elements associated with inversion polymorphisms in natural populations of Drosophila melanogaster. The model demonstrates that, if heterozygosity for an inversion effectively reduces element associated production of detrimental chromosome rearrangements, a differential accumulation of elements is expected, with increased copy number inside the minority inversion. Several-fold differential accumulations are possible with certain parameter values. We present data on P element counts for inversion polymorphisms on all five chromosome arms of 157 haploid genomes from two African populations. Our observations show significantly increased numbers of elements within the regions associated with the least common, or minority arrangements, in natural inversion polymorphisms.