Comparison of 2D fiber network orientation measurement methods
Comparison of 2D fiber network orientation measurement methods
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DOI：
10.1002/jbm.a.31847
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发表时间：
2009-02-01
影响因子：
4.9
通讯作者：
Barocas, V. H.
中科院分区：
文献类型：
--
作者：
Sander, E. A.;Barocas, V. H.
组织、组织类似物和生物材料的机械性能取决于其基本的微观结构。因此，许多力学模型包含了微结构的某些方面，但用于表征光纤结构的健壮协议仍然是一个挑战。许多基于图像的方法，包括平均截距长度(MIL)、线分数偏差(LFD)和傅立叶变换方法(FTM)，已经被应用于微结构图像来描述材料的非均质性和取向，但还没有进行性能比较，特别是对于光纤网络。在这项研究中，我们构建了40个二维测试图像，由模拟的纤维网络组成，这些网络在纤维数量、取向和各向异性指数方面都不同。我们评估了每种方法在测量主方向(Theta)和各向异性指数(α)方面的准确性。FTM被证明是更好的方法，因为它在测量精度上更可靠(Delta theta=2.95度+/-6.72度，Delta Alpha=0.03+/-0.02)，执行时间更快，应用更灵活。MIL(Delta theta=6.23度+/-10.68度，Delta Alpha=0.08+/-0.06)的准确度并不比FTM低很多，但要慢得多。LFD(Delta theta=9.97度+/-11.82度，Delta Alpha=0.24+/-0.13)一直表现不佳。FTM的结果与纤维蛋白凝胶扫描电子显微镜的结果定性一致，表明FTM可用于获得基于图像的微观结构统计测量。(C)2008 Wiley期刊，Inc.《生物材料杂志》88A：322-331,2009
The mechanical properties of tissues, tissue analogs, and biomaterials are dependent oil their underlying microstructure. As such, many mechanical models incorporate some aspect of microstructure, but a robust protocol for characterizing Fiber architecture remains a challenge. A number of image-based methods, including mean intercept length (MIL), line fraction deviation (LFD), and Fourier transform methods (FTM), have been applied to microstructural images to describe material heterogeneity and orientation, but a performance comparison, particularly for fiber networks, has not been conducted. In this study, we constructed 40 two-dimensional test images composed of simulated fiber networks varying in fiber number, orientation, and anisotropy index. We assessed the accuracy of each method in measuring principal direction (theta) and anisotropy index (alpha). FTM proved to be the superior method because it was more reliable in measurement accuracy (Delta theta = 2.95 degrees +/- 6.72 degrees, Delta alpha = 0.03 +/- 0.02), faster in execution time, and flexible in its application. MIL (Delta theta = 6.23 degrees +/- 10.68 degrees, Delta alpha = 0.08 +/- 0.06) was not significantly less accurate than FTM but was much slower. LFD (Delta theta = 9.97 degrees +/- 11.82 degrees, Delta alpha = 0.24 +/- 0.13) consistently underperformed. FTM results agreed qualitatively with fibrin gel SEM micrographs, suggesting that FTM can be used to obtain image-based statistical measurements of microstructure. (C) 2008 Wiley Periodicals, Inc. J Biomed Mater Res 88A: 322-331, 2009