Organogenesis: Molecular Mechanisms Of Tubulogenesis
Organogenesis: Molecular Mechanisms Of Tubulogenesis
复制标题
器官发生：管状发生的分子机制
DOI：
--
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发表时间：
2002
影响因子：
42.7
通讯作者：
P. Kolodziej
中科院分区：
文献类型：
--
作者：
B. Hogan;P. Kolodziej
As organisms have evolved in size and complexity, tubular systems have developed to enable the efficient transport of substances into and out of tissues. These tubular systems are generated using strategies that are based on common elements of cell behaviour, including cell polarization, tube migration to target sites, cell-fate diversification and localization of specialized cells to different regions of the tube system. Using examples from both invertebrate and vertebrate systems, this review highlights progress in understanding these basic principles and briefly discusses the possible evolution of strategies to regulate the morphogenesis of tubular systems.
