Cerebellar transcranial magnetic stimulation: The role of coil type from distinct manufacturers.
Cerebellar transcranial magnetic stimulation: The role of coil type from distinct manufacturers.
复制标题
小脑经颅磁刺激：不同制造商的线圈类型的作用。
DOI：
10.1016/j.brs.2019.09.005
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发表时间：
2020
影响因子：
7.7
通讯作者：
Spampinato D
中科院分区：
文献类型：
--
作者：
Spampinato D
背景用经颅磁刺激刺激小脑通常被认为是不舒服的。目的研究Magstim(70 mm、110 mm涂层、110 mm涂层)、MagVenture和Deymed不同线圈对小脑刺激效果的影响。方法采用小脑-脑抑制实验方法，根据受试者的最大耐受刺激强度(MTI)绘制CBI招募曲线，以评估每个线圈激活小脑的效果。在MTI中，Magstim(110 mm涂层/非涂层)和Deymed线圈产生了可靠的CBI，而MagVenture线圈没有发现CBI。这些结果可以指导设计小脑TMS研究时线圈的选择和刺激参数。
BackgroundStimulating the cerebellum with transcranial magnetic stimulation is often perceived as uncomfortable. No study has systematically tested which coil design can effectively trigger a cerebellar response with the least discomfort.ObjectiveTo determine the relationship between perceived discomfort and effectiveness of cerebellar stimulation using different coils: MagStim (70 mm, 110 mm-coated, 110-uncoated), MagVenture and Deymed.MethodsUsing the cerebellar-brain inhibition (CBI) protocol, we conducted a CBI recruitment curve with respect to each participant’s maximum tolerated-stimulus intensity (MTI) to assess how effective each coil was at activating the cerebellum.ResultsOnly the Deymed double-cone coil elicited CBI at low intensities (−20% MTI). At the MTI, the MagStim (110 mm coated/uncoated) and Deymed coils produced reliable CBI, whereas no CBI was found with the MagVenture coil.Conclusions: The Deymed double-cone coil was most effective at cerebellar stimulation at tolerable intensities. These results can guide coil selection and stimulation parameters when designing cerebellar TMS studies.