Selective slow-wave sleep (SWS) deprivation and SWS rebound: do we need a fixed SWS amount per night?
Selective slow-wave sleep (SWS) deprivation and SWS rebound: do we need a fixed SWS amount per night?
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选择性慢波睡眠 (SWS) 剥夺和 SWS 反弹：我们每晚需要固定的 SWS 量吗？
DOI：
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发表时间：
1999
期刊：
影响因子：
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通讯作者：
M. Bertini
中科院分区：
文献类型：
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作者：
M. Ferrara;L. Gennaro;M. Bertini
视觉评分δ活动（阶段3和4，SWS）以及计算机化的δ活动措施增加后，总和选择性睡眠剥夺。然而，SWS量是否仅是先前清醒持续时间的函数，或者它是否与先前睡眠期的结构有关（即，在SWS上花费的时间）。为了澄清SWS的量是否在确定SWS恢复中至关重要，我们在两个晚上选择性地剥夺SWS，以评估在接下来的恢复夜晚是否存在代偿性SWS反弹。10名正常男性在实验室中连续睡了6个晚上。经过适应和两个基线夜（BSL; BSL-A），选择性SWS剥夺完成了连续两个晚上（DEP-1; DEP-2），通过声刺激技术。然后是一个恢复（REC）的夜晚。几乎完全选择性SWS抑制在两个剥夺夜实现。与BSL-A相比，REC中S4和SWS的显著增加意味着S3和S4潜伏期的显著缩短。S2的百分比显着增加，在两个DEP的夜晚与其他实验的夜晚。夜间总睡眠时间、REM睡眠百分比、第1阶段、运动时间、觉醒次数和运动觉醒次数无显著差异，表明声刺激技术不会显著破坏正常睡眠的连续性和结构。这些结果表明，选择性SWS剥夺后的SWS反弹可以归因于连续两个晚上积累的SWS的损失，进一步支持了δ睡眠量与前一睡眠期的SWS的联系比与总睡眠时间的联系更紧密的观点。
Visually scored delta activity (stages 3 and 4, SWS) as well as computerized delta activity measures increase after total and selective sleep deprivation. It is, however, still controversial if SWS amount is only a function of prior waking duration, or if it is related to the structure of the previous sleep period (i.e., to the time spent in SWS). In order to clarify if the amount of SWS is crucial in determining SWS recovery, we selectively deprived SWS during two nights to assess the presence of a compensatory SWS rebound in the following recovery night. Ten normal males slept for 6 consecutive nights in the laboratory. After an adaptation and two baseline nights (BSL; BSL-A), selective SWS deprivation was accomplished for two consecutive nights (DEP-1; DEP-2), by means of an acoustic stimulation technique. A recovery (REC) night then followed. An almost complete selective SWS suppression during both deprivation nights was achieved. A significant increase of S4 and SWS in the REC as compared to the BSL-A paralleled a significant shortening of S3 and S4 latencies. S2 percentage significantly increased during both DEP nights with respect to the other experimental nights. There was no significant difference among nights with regard to total sleep time, percentage of REM sleep, stage 1, movement time, number of awakenings and number of movement arousals, indicating that the acoustic stimulation technique did not dramatically disrupt normal sleep continuity and architecture. These results indicate that SWS rebound after selective SWS deprivation can be ascribed to the loss of SWS accumulated during two consecutive nights, further supporting the idea that the delta sleep amount is more linked to SWS in the previous sleep periods than to the total sleep duration.