Clock genes, hair growth and aging.
Clock genes, hair growth and aging.
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DOI:
10.18632/aging.100130
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发表时间:
2010-03-31
期刊:
影响因子:
--
通讯作者:
Andersen B
中科院分区:
文献类型:
--
作者:
Geyfman M;Andersen B
Hair follicles undergo continuous cycles of growth, involution and rest. This process, referred to as the hair growth cycle, has a periodicity of weeks to months. At the same time, skin and hair follicles harbor a functional circadian clock that regulates gene expression with a periodicity of approximately twenty four hours. In our recent study we found that circadian clock genes play a role in regulation of the hair growth cycle during synchronized hair follicle cycling, uncovering an unexpected connection between these two timing systems within skin. This work, therefore, indicates a role for circadian clock genes in a cyclical process of much longer periodicity than twenty four hours.
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作者:
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