Engineered metal and their complexes for nanomedicine-elicited cancer immunotherapy
Engineered metal and their complexes for nanomedicine-elicited cancer immunotherapy
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DOI：
10.1016/j.mtadv.2022.100276
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发表时间：
2022-08-08
影响因子：
10
通讯作者：
Xiao, Haihua
中科院分区：
文献类型：
--
作者：
Wang, Yushu;Wang, Bin;Xiao, Haihua
Cancer immunotherapy, such as cancer vaccines and checkpoint blockades, has emerged as a promising cancer therapy in battling cancer, and revolutionized the field of cancer therapy. However, due to the low immune response, the clinical applications of immunotherapy have been greatly limited. As a classical category of anti-cancer drugs, metal and their complexes-based nanomedicine have already been extensively studied, and investigated as potential tools to enhance the anti-tumor immune response, in which they can reverse the immunosuppression without inducing toxicity or side effects. In this review, we summarize the-state-of-art metallic nanomedicine to enhance the efficacy of cancer immunotherapy. In the end, the obstacles and remaining challenges for metal-based nanomedicine are also summarized.(c) 2022 Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/).
