Disseminated intravascular coagulation complicating acute lymphoblastic leukemia: A study of childhood and adult cases
Disseminated intravascular coagulation complicating acute lymphoblastic leukemia: A study of childhood and adult cases
复制标题
DOI：
10.1080/10428190500102662
复制
发表时间：
2005-08-01
影响因子：
2.6
通讯作者：
Omine, M
中科院分区：
文献类型：
--
作者：
Higuchi, T;Toyama, D;Omine, M
成人急性淋巴细胞白血病（ALL）并发弥散性血管内凝血（DIC）的发病率较高。然而，包括儿童和成人患者的研究很少，急性淋巴细胞白血病患者DIC的临床相关性一直是一个相互矛盾的问题。研究了44例儿童和51例成人ALL患者就诊时和开始缓解诱导治疗后7天内的凝血功能。在就诊时，2名儿童（5%）和11名成人（22%）患者有DIC（p
A high incidence of disseminated intravascular coagulation (DIC) in adult patients with acute lymphoblastic leukemia (ALL) is reported. However, studies comprising both childhood and adult patients are sparse and the clinical relevance of DIC in ALL patients has been a conflicting issue. Coagulation profiles at presentation and within seven days after starting remission-induction therapy of 44 childhood and 51 adult ALL patients were studied. At presentation, two childhood (5%) and 11 adult (22%) patients had DIC (p